Nickel allergy and its relationship with local nickel pollution, ear piercing, and atopic dermatitis: A population-based study from Norway
| Autor: | Lars Kåre Dotterud, Tone Smith-Sivertsen, Eiliv Lund |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Adult
Male inorganic chemicals Nickel allergy medicine.medical_specialty Adolescent Population chemistry.chemical_element Air Pollutants Occupational Punctures Dermatology Dermatitis Atopic Sex Factors Ear piercing Nickel Risk Factors Confidence Intervals Prevalence otorhinolaryngologic diseases medicine Humans Ear External Risk factor education Aged education.field_of_study Norway business.industry Atopic dermatitis Middle Aged Patch Tests medicine.disease Confidence interval Surgery Cross-Sectional Studies chemistry Population Surveillance Relative risk Dermatitis Allergic Contact Metallurgy Multivariate Analysis Female business |
| Zdroj: | Journal of the American Academy of Dermatology. 40:726-735 |
| ISSN: | 0190-9622 |
| Popis: | Background: The north-Norwegian population of Sor-Varanger lives close to 2 Russian nickel smelters. Objective: We studied the importance of the local nickel pollution, as well as ear piercing and atopic dermatitis, on the prevalence of nickel allergy in Sor-Varanger. Methods: We patch-tested 1767 adults who were randomly selected from 2 different cross-sectional studies; in Sor-Varanger and the reference city of Tromso, which has no nickel-polluting industry. Results: Nickel allergy was diagnosed in 27.5% and 31.1% of the women in Sor-Varanger and Tromso, respectively, and in 5.1% and 5.0% of the men. In women, ear piercing was a strong risk factor (relative risk=3.30; 95% confidence interval=2.01 to 5.43). A history of atopic dermatitis was not associated with nickel sensitization. We found no increased risk of nickel allergy in Sor-Varanger compared with Tromso in adjusted multivariate analyses. Conclusion: The high prevalence of nickel allergy found in Sor-Varanger could not be attributed to pollution from the nearby nickel industry.(J Am Acad Dermatol 1999;40:726-35.) |
| Databáze: | OpenAIRE |
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