Human Growth Hormone Radioreceptor Assay using Cultured Human Lymphocytes
| Autor: | J R Gavin rd, Maxine A. Lesniak, Jesse Roth, Phillip Gorden |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
medicine.medical_specialty
Swine Growth hormone Binding Competitive General Biochemistry Genetics and Molecular Biology Hormone Receptor Interactions Radioligand Assay Biological specificity Species Specificity Iodine Isotopes Internal medicine Methods medicine Animals Humans Lymphocytes Cells Cultured Binding Sites Sheep Chemistry Human growth hormone Biological activity Radioimmunoassay General Medicine Prolactin Rats Endocrinology Growth Hormone Acromegaly Cattle Hormone |
| Zdroj: | Nature New Biology. 241:20-22 |
| ISSN: | 2058-1092 0090-0028 |
| Popis: | RADIOMMUNOASSAY has been widely applied to the measurement of circulating growth hormone. Although sensitive and precise methods for measuring immunoreactive growth hormone in plasma are available, there have been no methods for quantitatively measuring the biological activity of growth hormone. Hormone receptor interactions have been studied extensively (refs. 1 and 2 and further refs. in ref. 1) and precise sensitive methods have been developed for measuring the concentration of polypeptide hormones based on their interaction with a biological tissue3,4. These biological methods not only have the precision and frequently the sensitivity of the radioimmunoassay but in addition they have biological specificity. |
| Databáze: | OpenAIRE |
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