Association between long-term exposure to ambient air pollution and prevalence of diabetes mellitus among Malaysian adults

Autor: Stephen Ambu, Geok Lin Khor, Hamizatul Akmal Abd Hamid, Wan-Loy Chu, Ezahtulsyahreen Bt. Ab. Rahman, Maria Safura Mohamad, Shew Fung Wong, Joon Wah Mak, Nur Liana Ab Majid, Wan Shakira Rodzlan Hasani, Muhammad Fadhli bin Mohd Yussoff, Wan Ling Elaine Chan, Norazizah Ibrahim Wong, Poh Sin Yap, Zaleha Bt. M. Rashid, Hj. Tahir bin Aris
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adult
Male
Health
Toxicology and Mutagenesis
Air pollution exposure
Air pollution
Ozone (O3)
010501 environmental sciences
Overweight
medicine.disease_cause
Southeast asian
01 natural sciences
03 medical and health sciences
Young Adult
lcsh:RC963-969
0302 clinical medicine
Environmental health
Diabetes mellitus
medicine
Diabetes Mellitus
Prevalence
Humans
030212 general & internal medicine
0105 earth and related environmental sciences
Aged
Pollutant
Aged
80 and over
Air Pollutants
Nitrogen dioxide (NO2)
Ambient air pollution
business.industry
Research
lcsh:Public aspects of medicine
Diabetes
Public Health
Environmental and Occupational Health
Malaysia
lcsh:RA1-1270
Environmental Exposure
Middle Aged
Particular matters (PM10)
medicine.disease
Obesity
lcsh:Industrial medicine. Industrial hygiene
Female
Particulate Matter
Sulphur dioxide (SO2)
medicine.symptom
business
Zdroj: Environmental Health, Vol 19, Iss 1, Pp 1-12 (2020)
Environmental Health
DOI: 10.1186/s12940-020-00579-w
Popis: Background Malaysia has the highest rate of diabetes mellitus (DM) in the Southeast Asian region, and has ongoing air pollution and periodic haze exposure. Methods Diabetes data were derived from the Malaysian National Health and Morbidity Surveys conducted in 2006, 2011 and 2015. The air pollution data (NOx, NO2, SO2, O3 and PM10) were obtained from the Department of Environment Malaysia. Using multiple logistic and linear regression models, the association between long-term exposure to these pollutants and prevalence of diabetes among Malaysian adults was evaluated. Results The PM10 concentration decreased from 2006 to 2014, followed by an increase in 2015. Levels of NOx decreased while O3 increased annually. The air pollutant levels based on individual modelled air pollution exposure as measured by the nearest monitoring station were higher than the annual averages of the five pollutants present in the ambient air. The prevalence of overall diabetes increased from 11.4% in 2006 to 21.2% in 2015. The prevalence of known diabetes, underdiagnosed diabetes, overweight and obesity also increased over these years. There were significant positive effect estimates of known diabetes at 1.125 (95% CI, 1.042, 1.213) for PM10, 1.553 (95% CI, 1.328, 1.816) for O3, 1.271 (95% CI, 1.088, 1.486) for SO2, 1.124 (95% CI, 1.048, 1.207) for NO2, and 1.087 (95% CI, 1.024, 1.153) for NOx for NHMS 2006. The adjusted annual average levels of PM10 [1.187 (95% CI, 1.088, 1.294)], O3 [1.701 (95% CI, 1.387, 2.086)], NO2 [1.120 (95% CI, 1.026, 1.222)] and NOx [1.110 (95% CI, 1.028, 1.199)] increased significantly from NHMS 2006 to NHMS 2011 for overall diabetes. This was followed by a significant decreasing trend from NHMS 2011 to 2015 [0.911 for NO2, and 0.910 for NOx]. Conclusion The findings of this study suggest that long-term exposure to O3 is an important associated factor of underdiagnosed DM risk in Malaysia. PM10, NO2 and NOx may have mixed effect estimates towards the risk of DM, and their roles should be further investigated with other interaction models. Policy and intervention measures should be taken to reduce air pollution in Malaysia.
Databáze: OpenAIRE
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