Is Soft Tissue Laxity Associated with Tissue Metal Concentrations after Total Knee Arthroplasty?
| Autor: | Julie Lowell, William M. Mihalko, Steven M. Kurtz, Anita L. Kerkhof, Meredith Perkins, Christina M. Arnholt, Daniel W. MacDonald |
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| Rok vydání: | 2018 |
| Předmět: |
Chromium
Joint Instability Male musculoskeletal diseases Knee Joint Rotation Posterior displacement Total knee replacement Biomedical Engineering Total knee arthroplasty Periprosthetic Joint laxity Metal Cadaver Humans Knee Range of Motion Articular Arthroplasty Replacement Knee General Dentistry Aged Aged 80 and over Titanium business.industry Chemistry Soft tissue Cobalt Middle Aged musculoskeletal system Biomechanical Phenomena Prosthesis Failure External rotation Metals visual_art visual_art.visual_art_medium Female Knee Prosthesis Nuclear medicine business |
| Zdroj: | Journal of Long-Term Effects of Medical Implants. 28:79-85 |
| ISSN: | 1050-6934 |
| DOI: | 10.1615/jlongtermeffmedimplants.2018025386 |
| Popis: | Increased joint laxity is associated with excessive polyethylene wear, but the correlation between laxity and metal wear has not been established. Fifteen necropsy-retrieved primary total knee replacements were mounted into a custom knee-testing machine that measured anterior-posterior, varus-valgus, and internal-external rotational laxity at 0°, 30°, 60°, and 90° of flexion. Inductively coupled plasma-mass spectrometry analysis was performed to measure the cobalt (Co), chromium (Cr), and titanium (Ti) concentrations in periprosthetic tissue samples. Spearman's rank correlations were performed to determine whether a significant correlation (p < 0.05) existed between soft tissue laxity and tissue metal concentrations. At 0° flexion, decreased posterior displacement was negatively correlated with elevated Co and Cr concentrations. At 30° flexion, decreased external rotation and varus deflection was negatively correlated with elevated Ti concentrations. At 60° flexion, decreased anterior displacement was negatively correlated with elevated Cr concentrations and decreased varus deflection was negatively correlated with increased Ti concentrations. At 90° flexion, decreased anterior displacement was negatively correlated with elevated Co and Cr concentrations. To our knowledge, this is the first study to investigate the correlation between tissue metal concentration and laxity. Decreased laxity was associated with elevated metal concentrations in periprosthetic tissue. |
| Databáze: | OpenAIRE |
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