Anti-N-Methyl-d-Aspartate Receptor Encephalitis
| Autor: | Ming-Chi Lai, Te-Yu Hung, Ning-Hui Foo |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adolescent
Midazolam medicine.medical_treatment Receptors N-Methyl-D-Aspartate limbic encephalitis medicine Humans Hypnotics and Sedatives Immunologic Factors Pediatrics Perinatology and Child Health Receptor Anti-NMDA receptor encephalitis biology business.industry Limbic encephalitis orolingual dyskinesia lcsh:RJ1-570 Immunoglobulins Intravenous Electroencephalography lcsh:Pediatrics anti-NMDA receptor encephalitis Immunotherapy medicine.disease Magnetic Resonance Imaging Anti-N-Methyl-D-Aspartate Receptor Encephalitis Anti-Anxiety Agents nervous system Pediatrics Perinatology and Child Health Immunology biology.protein Encephalitis NMDA receptor Female Antibody business |
| Zdroj: | Pediatrics and Neonatology, Vol 52, Iss 6, Pp 361-364 (2011) |
| ISSN: | 1875-9572 |
| DOI: | 10.1016/j.pedneo.2011.08.012 |
| Popis: | Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a treatment-responsive encephalitis associated with anti-NMDA receptor antibodies, which bind to the NR1/NR2 heteromers of the NMDA receptors. It is a highly characteristic syndrome evolving in five stages: the prodromal phase (viral infection-like symptoms), psychotic phase, unresponsive phase, hyperkinetic phase, and gradual recovery phase. It has been considered as a paraneoplastic syndrome usually affecting childbearing-age female with ovarian tumors; however, recent reports suggest a much higher incidence of nonparaneoplastic cases in children. We report a 14-year-old girl with anti-NMDA receptor encephalitis without a detectable tumor who showed a nearly complete recovery after intensive immunotherapy. |
| Databáze: | OpenAIRE |
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