Human stretch reflex pathways reexamined
| Autor: | Kemal S. Türker, Natalie Mrachacz-Kersting, Ş. Utku Yavuz, Oğuz Sebik, M. Berna Ünver, Dario Farina |
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| Přispěvatelé: | Ege Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Recruitment Neurophysiological Reflex Stretch Physiology Isometric exercise Stimulus (physiology) Inhibitory postsynaptic potential peristimulus frequencygram EMG Isometric Contraction Neural Pathways medicine muscle spindle reflex Humans Stretch reflex human Muscle Skeletal Motor Neurons Leg General Neuroscience Articles Motor unit medicine.anatomical_structure Reflex Silent period Synaptic current Psychology peristimulus time histogram Neuroscience |
| Zdroj: | Yavuz, S U, Mrachacz-Kersting, N, Sebik, O, Unver, M B, Farina, D & Türker, K S 2014, ' Human stretch reflex pathways reexamined ', Journal of Neurophysiology, vol. 111, no. 3, pp. 602-612 . https://doi.org/10.1152/jn.00295.2013 Journal of Neurophysiology |
| DOI: | 10.1152/jn.00295.2013 |
| Popis: | WOS: 000331215500015 PubMed ID: 24225537 Reflex responses of tibialis anterior motor units to stretch stimuli were investigated in human subjects. Three types of stretch stimuli were applied (tap-like, ramp-and-hold, and half-sine stretch). Stimulus-induced responses in single motor units were analyzed using the classical technique, which involved building average surface electromyogram (SEMG) and peristimulus time histograms (PSTH) from the discharge times of motor units and peristimulus frequencygrams (PSF) from the instantaneous discharge rates of single motor units. With the use of SEMG and PSTH, the tap-like stretch stimulus induced five separate reflex responses, on average. With the same single motor unit data, the PSF technique indicated that the tap stimulus induced only three reflex responses. Similar to the finding using the tap-like stretch stimuli, ramp-and-hold stimuli induced several peaks and troughs in the SEMG and PSTH. The PSF analyses displayed genuine increases in discharge rates underlying the peaks but not underlying the troughs. Half-sine stretch stimuli induced a long-lasting excitation followed by a long-lasting silent period in SEMG and PSTH. The increase in the discharge rate, however, lasted for the entire duration of the stimulus and continued during the silent period. The results are discussed in the light of the fact that the discharge rate of a motoneuron has a strong positive linear association with the effective synaptic current it receives and hence represents changes in the membrane potential more directly and accurately than the other indirect measures. This study suggests that the neuronal pathway of the human stretch reflex does not include inhibitory pathways. Marie Curie Chair Project (GenderReflex)European Union (EU) [MEX-CT-2006-040317]; Turkish Scientific and Technological Research Organization GrantTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TUBITAK-107S029-SBAG-3556]; European Research Council Advanced GrantEuropean Research Council (ERC) [DEMOVE 267888]; Det Obelske Familiefond; Danish Government Scholarship Cultural Agreements [2010/11] This study is supported by Marie Curie Chair Project (GenderReflex) MEX-CT-2006-040317, Turkish Scientific and Technological Research Organization Grant TUBITAK-107S029-SBAG-3556, European Research Council Advanced Grant DEMOVE 267888, and the Det Obelske Familiefond. S. U. Yavuz, O. Sebik, and M. B. Unver are supported by Danish Government Scholarship Cultural Agreements 2010/11. K. S. Turker is a Fellow of the Turkish Academy of Sciences Association. |
| Databáze: | OpenAIRE |
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