Monitoring digoxin therapy: I. Plasma concentrations and an in vitro assay of tissue response
| Autor: | D. G. Grahame-Smith, F. M. Wigley, Jeffrey K Aronson, K F Hallis, Arthur Hibble |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Digoxin medicine.medical_specialty Erythrocytes Time Factors In Vitro Techniques Pharmacology Internal medicine medicine Humans Pharmacology (medical) cardiovascular diseases Aged Radioisotopes business.industry Arrhythmias Cardiac Atrial fibrillation Middle Aged Rubidium medicine.disease In vitro Endocrinology Plasma concentration Human erythrocytes Female business 86rb uptake Research Article medicine.drug |
| Popis: | 1 An in vitro technique is described for measuring the uptake of 86Rb by human erythrocytes. 2 Fifteen patients were treated with digoxin for atrial fibrillation and other fast arrhythmias. 3 86Rb uptake by the patients' own red cells fell from pre-treatment values during digitalization. 4 The therapeutic response of patients with atrial fibrillation correlated better with the changes in 86Rb uptake than with plasma digoxin concentrations. |
| Databáze: | OpenAIRE |
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