Serotipos prevalentes de Streptococcus pneumoniae colonizadores de nasofaringe, en niños del Distrito Federal
| Autor: | Fortino Solórzano-Santos, Gabriela Echániz-Aviles, Ma Guadalupe Miranda-Novales, Héctor Guiscafré-Gallardo, Araceli Soto-Noguerón, Laura Alicia Ortiz-Ocampo |
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| Jazyk: | Spanish; Castilian |
| Rok vydání: | 2005 |
| Předmět: |
Serotype
Cefotaxime business.industry Chloramphenicol Public Health Environmental and Occupational Health Salud colonización nasofaríngea Antimicrobial medicine.disease_cause Virology Microbiology Penicillin Streptococcus pneumoniae serotipos capsulares Ampicillin Medicine Vancomycin business medicine.drug |
| Zdroj: | Instituto Mexicano del Seguro Social IMSS Redalyc-IMSS Instituto Nacional de Salud Pública INSP Redalyc-INSP |
| Popis: | Objective. To determine the frequency, serotypes and susceptibility profiles to eight antimicrobials in Streptococcus pneumoniae nasopharyngeal isolates from a representative sample of children under 5 years of age, residents of Mexico City. Patients and Methods. A cross-sectional survey was conducted in 573 children aged 2 months to 5 years. A nasopharyngeal sample was taken. S. pneumoniae identification, capsular serotyping and antimicrobial susceptibility to eight antimicrobials were performed according to standardized methods Results. S. pneumoniae was isolated in 122/573 (21.4%) children. The most frequent capsular serotypes were 23F, 35, 19F, 11A and 15A; 46% of isolates corresponded to serotypes not included in the heptavalent vaccine. Low penicillin susceptibility was found in 12% of strains with 3% of highly resistant penicillin strains; erythromycin resistance was >30% and trimethoprim-sulfamethoxazole resistance >40%. None of the isolates was resistant to vancomycin, cefotaxime, amoxacillin-clavulanate, chloramphenicol or ampicillin. Conclusions. Several S. pneumoniae serotypes from nasopharyngeal carriers are not included in the heptavalent vaccine. Resistance to trimethoprim-sulfamethoxazole and macrolides is high. The medical community should be aware of these results. Solorzano-Santos F, Ortiz-Ocampo LA, Miranda-Novales MG, Echaniz-Aviles G, Soto-Nogueron A, Guiscafre-Gallardo H. Serotipos prevalentes de Streptococcus pneumoniae colonizadores de nasofaringe, en ninos del Distrito Federal. Salud Publica Mex 2005;47:276-281. |
| Databáze: | OpenAIRE |
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