| Autor: |
Susana Liwacki, Edgardo Reich, Marcela Parada Marcilla, Verónica Tkachuk, Patricio Blaya, Geraldine Luetic, Vladimiro Sinay, Gisela Zanga, Fatima Pagani Cassara, Norma Deri, Alejandro Caride, Pablo A. López, Ivan Martos, María C. Ysrraelit, Marcela Fiol, María Laura Menichini, Mariano Coppola, Edgar Carnero Contentti, Nora Fernández Liguori, Edgardo Cristiano, Gustavo Sgrilli, Ricardo Alonso, Andrés Barboza, Laura Negrotto, Luciano Recchia, Javier Pablo Hryb, Carlos Vrech, Raúl Piedrabuena, Jorge Correale, Maria Laura Saladino, Diego Giunta, Pablo Divi, Judith Steinberg, Dario Tavolini, Carolina Mainella, María I. Gaitán, Orlando Garcea, Pedro Nofal, Matías Kohler, Guido Vazquez, Marcos Burgos, María Eugenia Balbuena, Adriana Carrá, Juan Ignacio Rojas, Anibal Chertcoff, Emanuel Silva, Jimena Miguez, Juan Pablo Viglione, Eduardo Knorre, Berenice Silva, Juan Pablo Pettinicchi, Marina Alonso Serena, Liliana Patrucco, Jorge Blanche, Leila Cohen, Agustín Pappolla, Maria E. Fracaro, Mariano Marrodan, Amelia Alves Pinheiro, Santiago Bestoso, Cecilia Pita, María Celeste Curbelo, María. L. Doldan, Felisa Leguizamon, Luciana Lazaro, Gabriel Volman, Lorena M. Cabrera, Ruben Manzi, Santiago Tizio, Gustavo Jose, Fernando Caceres, Alejandra D. Martinez, Miguel Jacobo, Eduardo Kohler |
| Předmět: |
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| Zdroj: |
Web of Science |
| Popis: |
Like MS prevalence, oligoclonal bands (OCB) frequency seems to follow a latitudinal gradient. Argentina is extensive, latitude-wise, and previous studies have not found an MS prevalence latitudinal gradient. Our aim is to describe OCB prevalence in MS, clinically isolated syndrome (CIS) and radiologically isolated syndrome (RIS) patients included in the Argentinean MS and NMOSD registry (RelevarEM) and to investigate if it follows a latitudinal gradient.For each province, an average latitude was calculated, and OCB frequency was investigated. Multivariate logistical regression analysis and linear correlation were performed. Statistical analysis was repeated after excluding patients from centers using isoelectric focusing (IEF) in less than 95% of patients (CwIEF95).We included 2866 patients. OCB where positive in 73.9% of patients. No association or correlation were found between OCB and latitude of residence, even after excluding patients from (CwIEF95).OCB positivity does not follow a latitudinal gradient in Argentina. Also, OCB positivity is lower than described in other world regions. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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