Evaluation of energy metabolism in septic patients with and without AKI
| Autor: | Ana Cláudia Soncini Sanches, Daniela Ponce, Marina Nogueira Berbel Bufarah, Cassiana Regina de Góes, André Luis Balbi, Mariana Cassani de Oliveira |
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| Přispěvatelé: | Universidade Estadual Paulista (UNESP) |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Physiology Endocrinology Diabetes and Metabolism medicine.medical_treatment Energy metabolism lcsh:TX341-641 Clinical nutrition Biochemistry Gastroenterology law.invention Sepsis 03 medical and health sciences law Internal medicine medicine Resting energy expenditure Mechanical ventilation 030109 nutrition & dietetics Nutrition and Dietetics business.industry Public Health Environmental and Occupational Health Acute kidney injury University hospital medicine.disease Intensive care unit Surgery Energy expenditure business lcsh:Nutrition. Foods and food supply Food Science |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Nutrire, Vol 42, Iss 1, Pp 1-6 (2017) |
| Popis: | Background The determination of resting energy expenditure (REE) in critically ill patients could prevent complications such as hypo- and hyperalimentation. This study aims to describe the REE in septic patients with and without acute kidney injury (AKI) and compare the REE estimated by the Harris-Benedict equation (HB) with the REE measured by indirect calorimetry (IC). Methods Prospective and observational study was performed. Septic patients older than 18 years, undergoing mechanical ventilation, with or without AKI defined by KDIGO criteria, and admitted to the Intensive Care Unit of University Hospital from Brazil were included. The REE was estimated by HB equation and measured by the IC within 72 h after the diagnosis of sepsis and 7 days after the initial measure. Results Sixty-eight patients were evaluated, age was 62.5 ± 16.6 years, 64.7% were male, 63.2% had AKI, and SOFA was 9.8 ± 2.35. The measured REE was 1857.5 ± 685.32 kcal, while the estimated REE was 1514.8 ± 356.72 kcal, with adequacy of 123.5 ± 43%. Septic patients without AKI (n = 25) and with AKI (n = 43) had measured REE statistically higher than the estimated one (1855.0 (1631.75–2052.75) vs. 1551.0 kcal (1349.0–1719.25), p = 0.007 and 1868.0 (1219.5–2364.75) vs. 1388.0 kcal (1254.0–1665.5), p = 0.026, respectively). There was no significant difference between the two groups (with and without AKI) in measured and estimated REE (p = 0.63 and 0.64, respectively). There was no significant difference in evolutional REE (1845.95 ± 658.27 kcal vs. 1809.54 ± 755.08 kcal, p = 0.86). Conclusions The REE measured by IC was significantly higher than that estimated by HB equation in both septic with and without AKI. There was no significant difference in REE between the septic patients with and without AKI, suggesting that AKI does not influence the energy metabolism of septic patients. |
| Databáze: | OpenAIRE |
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