Lichenoid reaction to hepatitis B vaccination
| Autor: | Christina A Saywell, Richard A. Wittal, Steven Kossard |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Hepatitis B vaccine Adolescent Dermatology Diagnosis Differential Pathogenesis Liver disease Humans Medicine Hepatitis B Vaccines medicine.diagnostic_test business.industry Lichen Planus Middle Aged medicine.disease Vaccination stomatognathic diseases Immunization Skin biopsy Immunology Female Drug Eruptions Viral disease business Viral hepatitis Follow-Up Studies |
| Zdroj: | Australasian Journal of Dermatology. 38:152-154 |
| ISSN: | 1440-0960 0004-8380 |
| Popis: | Liver disease is now a well recognized association with lichen planus. Recent reports suggest that the hepatitis viruses may play a central role in this association. The present report describes a case of a lichenoid reaction to hepatitis B vaccination, which has only been rarely documented previously. A 16-year-old male developed a widespread pruritic erythematous eruption 5 weeks after receiving his second dose of hepatitis B vaccine. The eruption evolved to produce strikingly blue macules before spontaneously disappearing. A skin biopsy showed an intense lichenoid reaction. The hepatitis B surface antigen component of the vaccine is probably responsible for this reaction as well as for other rare immunologically mediated reactions to hepatitis B vaccination. These reactions may provide insight into the pathogenesis of the cutaneous features of natural hepatitis B infection. |
| Databáze: | OpenAIRE |
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