Seroprevalence of Helicobacter pylori Infection in Renal Transplant Recipient Attending Duhok Kidney Disease Center
Autor: | Amer A Balatay, Nashwan Ibrahim, A.A. Taha, Kais H Abd, Nawfal R Hussein, Mahde S. Assafi, Shameran Daniel, Zana Sidiq M. Saleem |
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Rok vydání: | 2015 |
Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Population Enzyme-Linked Immunosorbent Assay Disease Gastroenterology Helicobacter Infections Postoperative Complications Seroepidemiologic Studies Internal medicine medicine Prevalence Seroprevalence Humans education Dialysis Aged Transplantation education.field_of_study biology Helicobacter pylori business.industry Case-control study Middle Aged medicine.disease biology.organism_classification Kidney Transplantation Antibodies Anti-Idiotypic Case-Control Studies Iraq Surgery Female Kidney Diseases Gastritis medicine.symptom business Kidney disease |
Zdroj: | Transplantation proceedings. 48(1) |
ISSN: | 1873-2623 |
Popis: | Introduction Helicobacter pylori plays an important role in the development of gastritis, peptic ulcer disease, and gastric cancer in the general population. Although dyspeptic complaints are frequent in renal transplant subjects, the role of H pylori in such complaints is not clear. This study was conducted to examine the prevalence of H pylori infection in patients with renal transplant and its role in the development of upper gastrointestinal tract (GIT) symptoms. Materials and Methods We compared the prevalence of H pylori in 109 renal transplant subjects with the prevalence of 161 healthy volunteers using an enzyme-linked immunosorbent assay to measure anti-H pylori IgG. Then, within the transplant group, we stratified our data in accordance with different variables, including upper GIT symptoms, sex, education level, smoking, and dialysis history. Results The prevalence of H pylori in the control group was 111 of 161 (68.9%), which was significantly higher than that found in renal transplant subjects (48/109; 43.04%; P = .001). Within the transplant group, no association was found between immunoglobulin G positivity and different variables including upper GIT symptoms, sex, education level, smoking, and dialysis history. Conclusions The prevalence of H pylori was lower in transplant subjects than that of general population. Upper GIT symptoms were equally found in both groups. Hence, the routine eradication of H pylori might not be indicated. |
Databáze: | OpenAIRE |
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