The role of endobronchial and endoscopic ultrasound guided fine needle aspiration for mediastinal nodal staging of non-small-cell lung cancer
| Autor: | Sebnem Gursoy, Işın Güneş, Inci Gulmez, Alper Yurci, Nuri Tutar, Özlem Canöz, Ömer Önal |
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| Rok vydání: | 2018 |
| Předmět: |
Male
0301 basic medicine Pulmonary and Respiratory Medicine Endoscopic ultrasound medicine.medical_specialty Lung Neoplasms Nodal staging Critical Care and Intensive Care Medicine 03 medical and health sciences 0302 clinical medicine Carcinoma Non-Small-Cell Lung Bronchoscopy Carcinoma Humans Medicine Lung cancer Endoscopic Ultrasound-Guided Fine Needle Aspiration neoplasms Aged Neoplasm Staging Retrospective Studies medicine.diagnostic_test business.industry Mediastinum Reproducibility of Results Retrospective cohort study Middle Aged medicine.disease respiratory tract diseases 030104 developmental biology medicine.anatomical_structure Fine-needle aspiration Lymphatic Metastasis 030220 oncology & carcinogenesis Female Surgery Lymph Nodes Radiology Lymph business |
| Zdroj: | Tuberkuloz ve Toraks. 66:85-92 |
| ISSN: | 0494-1373 |
| Popis: | Introduction Mediastinal and hilar nodal staging is one of the key points for differentiating treatment modalities in patients with non-small-cell lung cancer (NSCLC). The aim of the present study was to determinate the diagnostic yields of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) and combined EBUS-TBNA and EUS-FNA modalities for nodal staging in potentially operable NSCLC patients. Materials and methods Twenty consecutive patients were prospectively enrolled in the study between March 2014 and November 2015. All patients had a potentially operable NSCLC diagnosis before endosonographic procedures. Result Thirty lymph nodes were sampled by EBUS-TBNA and 17 lymph nodes were sampled by EUS-FNA in all 20 patients. The sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of F-18 fluorodeoxyglucose positron emission tomography with computed tomography (PET-CT), EBUS-TBNA, EUS-FNA and combined EBUS-TBNA and EUS-FNA were 100%, 33.3%, 64.7%, 100% and 70.0%; 81.8%, 100%, 100%, 81.8% and 90%; 81.8%, 100%, 100%, 75% and 88.2%; 90.9%, 100%, 100%, 90.0% and 95.0%, respectively. Conclusions The combined EBUS-TBNA and EUS-FNA technique is a successful procedure for nodal staging in potentially operable NSCLC patients. |
| Databáze: | OpenAIRE |
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