Debittering of lemon juice using surface molecularly imprinted polymers and the utilization of limonin
Autor: | Guocan Zheng, Chong-Zhi Wang, Yu-Zhen Zhang, Zhining Xia, Lian-Di Zhou, Jia-Wei Zhang, Qi-Hui Zhang, Chun-Su Yuan, Ling Tan |
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Rok vydání: | 2019 |
Předmět: |
Limonins
Citrus Sorbent Limonin Clinical Biochemistry 030226 pharmacology & pharmacy 01 natural sciences Biochemistry High-performance liquid chromatography Analytical Chemistry Molecular Imprinting Mice 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Adsorption Animals chemistry.chemical_classification Wound Healing Chromatography 010401 analytical chemistry Molecularly imprinted polymer Cell Biology General Medicine Polymer 0104 chemical sciences Fruit and Vegetable Juices chemistry Polymerization Selectivity |
Zdroj: | Journal of Chromatography B. 1104:205-211 |
ISSN: | 1570-0232 |
Popis: | In this work, surface molecularly imprinted polymers (SMIPs) were prepared as a specific sorbent to remove the limonin from the lemon juice for the first time, and then the MIPs containing limonin were directly made into a water-soluble gel to treat inflammation of mice. The resulting polymers were characterized by scanning electron microscopy, transmission electron microscopy and Fourier transform infrared spectrometer spectra. And the polymerization conditions and adsorption performances of the resultant nanomaterials were further investigated in detail. Results showed that the MIPs have higher adsorption capacity (27.72 mg/g) compared with surface molecularly non-imprinted polymers (NIPs) (8.12 mg/g). The selectivity experiment indicated that the polymers had excellent selective recognition for limonin and the selectivity factors were calculated as 2.75 and 1.83 for nomilin and obakunone, respectively. The MIPs were successfully used as adsorbent for selectively removing limonin from lemon juice and the MIPs extracted almost all the limonin from lemon juice according to the HPLC results. Furthermore, the MIPs with limonin were processed into water-soluble gel, which can be used to reduce the inflammation and enhance wound healing of model mice. |
Databáze: | OpenAIRE |
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