Metal-ion nucleic-acid interactions: A personal account
| Autor: | Reedijk, J. |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Personal account
010405 organic chemistry Base pair Hydrogen bond Chemistry Inorganic chemistry Context (language use) 010402 general chemistry 01 natural sciences Combinatorial chemistry 0104 chemical sciences Inorganic Chemistry Metal visual_art Materials Chemistry visual_art.visual_art_medium Nucleic acid Physical and Theoretical Chemistry |
| Zdroj: | Inorganica Chimica Acta. 452:268-272 |
| ISSN: | 0020-1693 |
| DOI: | 10.1016/j.ica.2015.12.011 |
| Popis: | A brief personal account is given on how I observed and enjoyed studying metal-ion nucleic-acid binding over the last 40 years, based on contributions from my own group and from our collaborators and competitors.Metal ions do bind to ligands, and the nucleic acids not only can act as metal-binding ligands, but also as hydrogen-bonding species, as typically known for Watson-Crick base pairs. In the study of metal nucleic acid binding, coordination and hydrogen bonding do often occur together and may act synergistically. In this account I will highlight a selection of our most important findings within the context of this special issue. (C) 2015 Elsevier B.V. All rights reserved. |
| Databáze: | OpenAIRE |
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