Asymmetric Suzuki-Miyaura cross-coupling of 1-bromo-2-naphthoates using the helically chiral polymer ligand PQXphos
| Autor: | Takeshi Yamamoto, Yuto Akai, Laure Konnert, Michinori Suginome |
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| Rok vydání: | 2015 |
| Předmět: |
Models
Molecular Stereochemistry Polymers Carboxylic Acids Molecular Conformation Naphthalenes Ligands Catalysis chemistry.chemical_compound Bromide Polymer chemistry Materials Chemistry Coupling chemistry.chemical_classification Ligand Metals and Alloys Helical polymer Stereoisomerism General Chemistry Polymer Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry Ceramics and Composites Enantiomer Chirality (chemistry) |
| Zdroj: | Chemical communications (Cambridge, England). 51(33) |
| ISSN: | 1364-548X |
| Popis: | A single-handed helical polymer ligand PQXphos afforded axially chiral biaryl esters with high enantioselectivities in asymmetric Suzuki–Miyaura cross-coupling. The use of naphthyl bromide bearing a 2,4-dimethyl-3-pentyl ester resulted in both high yields and high enantioselectivities. Either enantiomer could be synthesized selectively by using a single PQXphos through a solvent-dependent switch of the helical chirality. |
| Databáze: | OpenAIRE |
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