Some new findings on the potential use of biocompatible silver nanoparticles in winemaking
| Autor: | Irene Gil-Sánchez, Carolina Cueva, Beatriz Miralles, Dolores González de Llano, Gloria Armentia, Begoña Bartolomé, Julian Crespo, Miguel Monge, M. Elena Olmos, Jose M. López de Luzuriaga, Ma Victoria Moreno-Arribas |
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| Přispěvatelé: | Ministerio de Economía, Industria y Competitividad (España), European Commission, Comunidad de Madrid, Ministerio de Educación, Cultura y Deporte (España), Universidad de Cantabria |
| Rok vydání: | 2019 |
| Předmět: |
inorganic chemicals
Wine bacteria Population B. Bruxellens Nanoparticle Polyethylene glycol Bacterial growth Industrial and Manufacturing Engineering Silver nanoparticle chemistry.chemical_compound mental disorders Sulphur dioxide alternatives education health care economics and organizations Winemaking Wine education.field_of_study Chemistry technology industry and agriculture General Chemistry respiratory system Antimicrobial Chemical engineering Silver nanoparticles Food Science |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| ISSN: | 1466-8564 |
| Popis: | There is currently an increasing commercial demand for silver nanoparticles (Ag NPs) due to their wide applicability in various markets. Because of their powerful antimicrobial properties, these nanoparticles are frequently used for food-associated consumer products. In this paper, the effect of two Ag NPs coated with biocompatible materials – PEG-Ag NPs 20 (polyethylene glycol) and GSH-Ag NPs (reduced glutathione) – to control microbial growth in wines was assessed. Both Ag NPs were subjected to an in vitro three-step digestion, and changes in their morphology and an assessment of their cytotoxicity against Caco-2 cells were determined. Both Ag NPs were effective against the different microbial population present in tested wines. Regarding their in vitro digestion, the size and shape of the nanoparticles were almost unaltered in the case of GSH-Ag NPs, while in PEG-Ag NPs 20 some particle agglomeration was observed. Overall, these results suggest that Ag NPs may reach the intestine in a nano-scaled form. Finally, Caco-2 cell experiments seemed to exclude toxicity of Ag NPs at the intestinal epithelium. This work was carried out with the financial support of the Spanish Ministry of Economy, Industry and Competitiveness (PRI-PIBAR-2011-1358, AGL2015-64522-C2-1 and D.G.I. (MEC)/FEDER CTQ2016-75816-C2-2-P projects), and the Comunidad de Madrid Program (ALIBIRD-CM S2013/ABI-2728). Authors acknowledge AGROVIN, S.L. for the technical assistance in some Brettanomyces experiments and TEM-SERMET Universidad de Cantabria for TEM images. I.G-S is the recipient of fellowships from the Spanish FPU-MECD (FPU14/05760) programme. |
| Databáze: | OpenAIRE |
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