Characterization of muscarine receptors in rabbit ciliary body smooth muscle using propylbenzilylcholine mustard
| Autor: | Katsuo Koike, Issei Takayanagi, Kiyoshige Saito, Mitsutoshi Satoh |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Male
medicine.medical_specialty Carbachol In Vitro Techniques Propylbenzilylcholine Mustard chemistry.chemical_compound Ciliary body Smooth muscle Internal medicine Muscarinic acetylcholine receptor medicine Animals Receptor Pharmacology Muscarine Lagomorpha biology Ciliary Body Muscle Smooth biology.organism_classification Receptors Muscarinic In vitro Endocrinology medicine.anatomical_structure chemistry Rabbits medicine.drug |
| Zdroj: | General pharmacology. 22(5) |
| ISSN: | 0306-3623 |
| Popis: | 1. A piece of rabbit ciliary body was mounted in organ bath and used as a test organ containing muscarine receptors. 2. A concentration response curve of carbachol was completely inhibited by a 50 min treatment of the smooth muscle preparation with propylbenzilylcholine mustard(PrBCM; 10(-6) M). This treatment was reported to block PrBCM-sensitive muscarine receptors in intestinal smooth muscle completely. 3. It is suggested that an existance of only PrBCM-sensitive muscarinic receptors, though there are two subtypes of muscarine receptors; PrBCM-sensitive and -resistant ones in intestinal smooth muscles. |
| Databáze: | OpenAIRE |
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