Effectiveness of a Web-Based Tailored Intervention With Virtual Assistants Promoting the Acceptability of HPV Vaccination Among Mothers of Invited Girls

Autor: Maxine E. A. Spoelstra, M. Pot, Hilde M. van Keulen, T. Paulussen, Robert A. C. Ruiter, Hester E. de Melker, Iris Eekhout
Přispěvatelé: Epidemiology and Data Science, CCA - Cancer biology and immunology, AII - Infectious diseases, Section Applied Social Psychology, RS: FPN WSP II
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Journal of Medical Internet Research, 19(9):e312. Journal of medical Internet Research
Journal of Medical Internet Research, 19(9):e312. JMIR Publications Inc.
Pot, M, Paulussen, T G W M, Ruiter, R A C, Eekhout, I, De Melker, H E, Spoelstra, M E A & Van Keulen, H M 2017, ' Effectiveness of a web-based tailored intervention with virtual assistants promoting the acceptability of hpv vaccination among mothers of invited girls : Randomized controlled trial ', Journal of Medical Internet Research, vol. 19, no. 9, e312 . https://doi.org/10.2196/jmir.7449
ISSN: 1438-8871
Popis: Background In 2010, the human papillomavirus (HPV) vaccination was introduced in the Dutch National Immunization Program for 12-year-old girls, aiming to reduce the incidence of cervical cancer in women. HPV vaccination uptake turned out to be lower than expected: 61% versus 70%, respectively. Mothers were shown to play the most important role in the immunization decision about this vaccination. They had also expressed their need for interactive personal information about the HPV vaccination over and above the existing universal general information. To improve the effectiveness of the existing education about the HPV vaccination, we systematically developed a Web-based tailored intervention with virtual assistants providing mothers of girls to be invited with tailored feedback on their decision making about the HPV vaccination. Objective The aim of this study was to evaluate the effectiveness of the Web-based tailored intervention for promoting HPV vaccination acceptance by means of a randomized controlled trial (RCT). Methods Mothers were recruited via the Dutch vaccination register (Praeventis) (n=36,000) and three Web-based panels (n=2483). Those who gave informed consent (N=8062) were randomly assigned to the control (n=4067) or intervention condition (n=3995). HPV vaccination uptake, as registered by Praeventis once the HPV vaccination round was completed, was used as the primary outcome. Secondary outcomes were differential scores across conditions between baseline (before the provided access to the new tailored intervention) and follow-up (just before the first vaccination) regarding the mothers’ degree of informed decision making (IDM), decisional conflict, and critical determinants of HPV vaccination uptake among which are intention, attitude, risk perception, and outcome beliefs. Results Intention-to-treat analysis (N=8062) showed a significant positive effect of the intervention on IDM, decisional conflict, and nearly all determinants of HPV vaccination uptake (P Conclusions This computer-tailored intervention has the potential to improve HPV vaccination acceptability and IDM and to decrease decisional conflict among mothers of invited girls. Implications for future research are discussed. Trial Registration Trialregister.nl NTR4935; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=4935 (Archived by WebCite at http://www.webcitation.org/6srT7l9EM)
Databáze: OpenAIRE
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