Novel pathogens in periodontal microbiology
Autor: | P Sudhakar, M V Ramoji Rao, K Sirisha, K Vidya Hiranmayi |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
030106 microbiology Slackia exigua polymicrobial infection lcsh:Analytical chemistry lcsh:RS1-441 Bioengineering Review Article Disease General Biochemistry Genetics and Molecular Biology Microbiology lcsh:Pharmacy and materia medica 03 medical and health sciences medicine General Pharmacology Toxicology and Pharmaceutics periodontitis Periodontitis lcsh:QD71-142 biology Dialister pneumosintes biology.organism_classification medicine.disease Novel microbiota 030104 developmental biology Oral microbiology Solobacterium moorei Treponema lecithinolyticum Cryptobacterium curtum |
Zdroj: | Journal of Pharmacy and Bioallied Sciences, Vol 9, Iss 3, Pp 155-163 (2017) Journal of Pharmacy & Bioallied Sciences |
ISSN: | 0975-7406 |
Popis: | Periodontitis is a polymicrobial disease caused by complex interactions between distinct pathogens in a biofilm resulting in the destruction of periodontal tissues. It seems evident that unknown microorganisms might be involved in onset or progression of periodontitis. For many decades, research in the field of oral microbiology failed to identify certain subgingival microbiota due to technical limitations but, over a period of 12 years using molecular approaches and sequencing techniques, it became feasible to reveal the existence of new periodontal pathogens. Therefore, it is evident that in addition to conventional periodontal pathogens, other microbes might be involved in onset and progression of periodontitis. The novel pathogens enlisted under periodontal phylogeny include Cryptobacterium curtum, Dialister pneumosintes, Filifactor alocis, Mitsuokella dentalis, Slackia exigua, Selenomonas sputigena, Solobacterium moorei, Treponema lecithinolyticum, and Synergistes. The polymicrobial etiology of periodontitis has been elucidated by comprehensive techniques, and studies throwing light on the possible virulence mechanisms possessed by these novel periodontal pathogens are enlisted. |
Databáze: | OpenAIRE |
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