Characterization of two related Erwinia myoviruses that are distant relatives of the PhiKZ-like Jumbo phages
| Autor: | Kerri A. Russell, Steven M. Johnson, Michelle H. Townsend, Olivia B. Tateoka, John L. Carter, Daniel K. Arens, Lyndsay A. Staley, Jason M. Stettler, Jenny A. Pape, T. Scott Brady, Trevor M. Wienclaw, Taryn L. Williamson, Kiara V. Whitley, D. Robinson, Julianne H. Grose |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Bacterial Diseases
Models Molecular 0301 basic medicine Proteome viruses lcsh:Medicine Erwinia Genome Viral Packaging Database and Informatics Methods Putative gene Medicine and Health Sciences Bacteriophages lcsh:Science Genetics Viral Genomics Multidisciplinary biology Genomics Enterobacteriaceae Infectious Diseases Enterobacter Infections Malus Myoviridae Viruses Sequence Analysis Research Article Bioinformatics 030106 microbiology Microbial Genomics Genome Viral Research and Analysis Methods Microbiology Host Specificity Viral Proteins 03 medical and health sciences Microscopy Electron Transmission Sequence Motif Analysis Pseudomonas Virology Gene Vibrio Bacteria lcsh:R Organisms Biology and Life Sciences biology.organism_classification Viral Replication lcsh:Q |
| Zdroj: | PLoS ONE, Vol 13, Iss 7, p e0200202 (2018) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | Bacteriophages are a major force in the evolution of bacteria due to their sheer abundance as well as their ability to infect and kill their hosts and to transfer genetic material. Bacteriophages that infect the Enterobacteriaceae family are of particular interest because this bacterial family contains dangerous animal and plant pathogens. Herein we report the isolation and characterization of two jumbo myovirus Erwinia phages, RisingSun and Joad, collected from apple trees. These two genomes are nearly identical with Joad harboring two additional putative gene products. Despite mass spectrometry data that support the putative annotation, 43% of their gene products have no significant BLASTP hit. These phages are also more closely related to Pseudomonas and Vibrio phages than to published Enterobacteriaceae phages. Of the 140 gene products with a BLASTP hit, 81% and 63% of the closest hits correspond to gene products from Pseudomonas and Vibrio phages, respectively. This relatedness may reflect their ecological niche, rather than the evolutionary history of their host. Despite the presence of over 800 Enterobacteriaceae phages on NCBI, the uniqueness of these two phages highlights the diversity of Enterobacteriaceae phages still to be discovered. |
| Databáze: | OpenAIRE |
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