Continuous intraarterial infusion of prostaglandin E1 and heparin to extend and improve the survival of pedicled musculocutaneous flaps through unusual routes: a clinical preliminary report
| Autor: | Yuji Sakaguchi, Masahiko Noguchi, Kiyoshi Matsuo, Takeshi Fujiwara, Hideo Kushima |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Adult
medicine.medical_specialty Serratus anterior muscle Mammaplasty Free flap Pectoralis Muscles chemistry.chemical_compound Thoracic Arteries medicine.artery medicine Humans Infusions Intra-Arterial Superficial epigastric artery Alprostadil Prostaglandin E1 Vascular Patency Abdominal Muscles Aged Lateral thoracic artery business.industry Heparin Muscles Graft Survival Thrombosis Pedicled Flap Skin Transplantation medicine.disease Cannula eye diseases Surgery body regions chemistry Anesthesia Axilla Female business Mastectomy Radical |
| Zdroj: | Annals of plastic surgery. 29(4) |
| ISSN: | 0148-7043 |
| Popis: | Sixteen pedicled musculocutaneous flaps (pectoralis major, 3; latissimus dorsi, 4; and transverse rectus abdominis musculocutaneous [TRAM], 9) received continuous intraarterial infusion of prostaglandin E1 (5 micrograms/k of flap per day) and heparin (100 to 200 U/cannula per day) for 14 days postoperatively to extend the flap or improve survival in a high-risk patient. Therapy was successful in 15 patients. To preserve the main arterial inflow to the flap, the infusion was administered via the lateral thoracic artery in the pectoralis major and a branch to the serratus anterior muscle in latissimus dorsi flaps in retrograde fashion, respectively, and was via both the ipsilateral deep epigastric artery and the contralateral superficial epigastric artery in TRAM flaps. This technique permits the use of a pedicled flap in some patients who would otherwise require a free flap. |
| Databáze: | OpenAIRE |
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