Fidaxomicin Therapy in Critically Ill Patients with Clostridium difficile Infection
| Autor: | Yanina Dubrovskaya, Amar Safdar, Samuel Penziner, Robert Press |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Multivariate analysis Critical Illness Disease Clinical Therapeutics Patients' Rooms medicine Humans Pharmacology (medical) Fidaxomicin Intensive care medicine Pharmacology Critically ill business.industry Clostridioides difficile Clostridium Infections Clostridium difficile Middle Aged Antibiotic coverage Anti-Bacterial Agents Patient room Infectious Diseases Aminoglycosides Female business medicine.drug |
| Popis: | Fidaxomicin use to treat proven Clostridium difficile infection (CDI) was compared between 20 patients receiving care in critical care units (CCUs) and 30 patients treated on general medical floors. At baseline, the CCU patients had more initial CDI episodes, more severe and complicated disease, and more concurrent broad-spectrum antibiotic coverage. On multivariate analysis, the response to fidaxomicin therapy among the critically ill patients was comparable to that among patients in the general medical wards. |
| Databáze: | OpenAIRE |
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