In VitroBinding characteristics for cesium of two qualities of prussian blue, activated charcoal and Resonium-A
| Autor: | J. M. Verzijl, T. J. F. Savelkoul, B. Sangster, J. H. Glerum, J. C.A. Joore, A. van Dijk, A.D. van het Schip |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Langmuir
Health Toxicology and Mutagenesis medicine.medical_treatment Inorganic chemistry chemistry.chemical_element In Vitro Techniques Toxicology chemistry.chemical_compound medicine Antidote Charcoal Prussian blue Hydrogen-Ion Concentration Hemoperfusion chemistry Activated charcoal Cesium Radioisotopes Caesium visual_art visual_art.visual_art_medium Polystyrenes Sodium Polystyrene Sulfonate Ferrocyanides Nuclear chemistry Activated carbon medicine.drug |
| Zdroj: | Journal of Toxicology: Clinical Toxicology. 30:215-222 |
| ISSN: | 0731-3810 |
| DOI: | 10.3109/15563659209038633 |
| Popis: | The in vitro binding characteristics of radioactive 137Cs to two forms of Prussian blue [colloidally (soluble) K3Fe[Fe(CN)6] and insoluble Fe4[Fe(CN)6]3] and to activated charcoal and sodium polystyrene sulfonate (Resonium-A) were investigated by constructing Langmuir isotherms at pH = 1.0, 6.5 and 7.5 at 37 degrees C. At the three pHs investigated, 137Cs binding to activated charcoal and sodium polystyrene sulfonate was negligible. Binding of 137Cs to insoluble Prussian blue exceeded that for the soluble form and was pH dependent for both formulations. Maximum binding capacities were 87 mg/g (pH = 1.0), 194 mg/g (pH = 6.5) and 238 mg/g (pH = 7.5) for the insoluble form and 48 (pH = 1.0), 73 (pH = 6.5) and 78 (pH = 7.5) for the soluble form. As activated charcoal did not bind 137Cs, charcoal hemoperfusion is of no value. This has been confirmed by an in vitro experiment, using a Gambro Adsorbs 300 C cartridge. |
| Databáze: | OpenAIRE |
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