Self-Reported Sexual Function in Sexually Active Male Hodgkin Lymphoma Survivors
Autor: | Josée M. Zijlstra, Otto Visser, Irma M. Verdonck-de Leeuw, Birgit I. Lissenberg-Witte, Luca Incrocci, Sonja Zweegman, Corien Eeltink, A.M.J. Braamse |
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Přispěvatelé: | Medical Psychology, CCA - Cancer Treatment and Quality of Life, APH - Mental Health, Clinical Psychology, Radiation Oncology, Hematology, Epidemiology and Data Science, CCA - Cancer Treatment and quality of life, Otolaryngology / Head & Neck Surgery, APH - Personalized Medicine, APH - Methodology |
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
BEACOPP
Vincristine medicine.medical_specialty Alkylating Chemotherapy Sexual Dysfunction Urology Endocrinology Diabetes and Metabolism medicine.medical_treatment Dacarbazine 030232 urology & nephrology lcsh:Medicine Dermatology 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine Endocrinology Erectile Dysfunction SDG 3 - Good Health and Well-being Prednisone Internal medicine medicine Sexual Function Chemotherapy 030219 obstetrics & reproductive medicine SDG 5 - Gender Equality business.industry Hodgkin Lymphoma lcsh:R lcsh:Other systems of medicine lcsh:RZ201-999 medicine.disease Psychiatry and Mental health Erectile dysfunction Sexual dysfunction Reproductive Medicine Oncology medicine.symptom Sexual function business medicine.drug Sexual Satisfaction |
Zdroj: | SEXUAL MEDICINE, 8(3), 428-435. Elsevier Inc. Sexual medicine, 8(3), 428-435. Elsevier Inc. Sexual Medicine, 8(3), 428-435. Elsevier Inc. Eeltink, C M, Lissenberg-Witte, B I, Incrocci, L, Braamse, A M J, Visser, O, Zijlstra, J, Verdonck-de Leeuw, I M & Zweegman, S 2020, ' Self-Reported Sexual Function in Sexually Active Male Hodgkin Lymphoma Survivors ', Sexual medicine, vol. 8, no. 3, pp. 428-435 . https://doi.org/10.1016/j.esxm.2020.04.005 Sexual Medicine Sexual Medicine, Vol 8, Iss 3, Pp 428-435 (2020) |
ISSN: | 2050-1161 |
Popis: | Introduction Unambiguous data on sexual dysfunction after Hodgkin lymphoma (HL) treatment are scarce. Aims To form a baseline in this area, we compared patient-reported sexual function in sexually active male HL survivors in complete remission with a sexually active, age-matched, male Dutch sample population. Furthermore, we explored whether sociodemographic and clinical factors were associated with sexual dysfunction in HL survivors and investigated whether reporting to perceive sexual problems was indicative for sexual dysfunction. Methods This cross-sectional study included male patients with HL who were treated with chemotherapy and age-matched sexually active males. Main outcome measures Outcome measures included the internationally validated International Index of Erectile Function (IIEF) and self-reported sexual problems by adding 3 items to the study-specific questionnaire. Results Erectile dysfunction (ED) occurred in 23.3% of the HL survivors vs in 23.0% of controls: respectively 13.3% and 12.3% had moderate to severe ED. However, more HL survivors positively answered the question whether they did perceive sexual problems than controls (20.0% vs 7.0%; P = .087). More patients treated with bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procabazine, and prednisone (BEACOPP) had sexual problems 33.3% vs 8.3% who were treated with doxorubicin, bleomycin, vinblastine, and dacarbazine (P = .057). Importantly, we found that the mean IIEF score for erectile function was 15.7 in HL survivors who reported to perceive sexual problems (moderate ED) vs 28.3 (normal) in those without perceiving sexual problems. Conclusion In general, sexual function of male HL survivors is comparable to that of matched normal controls. Perceiving sexual problems was associated with lower sexual function measured by the IIEF. None of the HL survivors who were treated with doxorubicin, bleomycin, vinblastine, and dacarbazine perceived sexual problems. However, one-third of HL survivors who were treated with BEACOPP did, including ED in one-third of the cases. This is an important consideration for daily clinical practice as BEACOPP is increasingly used as standard therapy in advanced-stage HL. |
Databáze: | OpenAIRE |
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