Occupation and Risk of Non-Hodgkin Lymphoma and Its Subtypes: A Pooled Analysis from the InterLymph Consortium
Autor: | 't Mannetje, Andrea, De Roos, Anneclaire J, Boffetta, Paolo, Vermeulen, Roel, Benke, Geza, Fritschi, Lin, Brennan, Paul, Foretova, Lenka, Maynadié, Marc, Becker, Nikolaus, Nieters, Alexandra, Staines, Anthony, Campagna, Marcello, Chiu, Brian, Clavel, Jacqueline, de Sanjose, Silvia, Hartge, Patricia, Holly, Elizabeth A, Bracci, Paige, Linet, Martha S, Monnereau, Alain, Orsi, Laurent, Purdue, Mark P, Rothman, Nathaniel, Lan, Qing, Kane, Eleanor, Seniori Costantini, Adele, Miligi, Lucia, Spinelli, John J, Zheng, Tongzhang, Cocco, Pierluigi, Kricker, Anne, dIRAS RA-I&I RA, dIRAS RA-2, LS IRAS EEPI GRA (Gezh.risico-analyse) |
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Přispěvatelé: | dIRAS RA-I&I RA, dIRAS RA-2, LS IRAS EEPI GRA (Gezh.risico-analyse), t Mannetje, A., De Roos, A.J., Boffetta, P., Vermeulen, R., Benke, G., Fritschi, L., Brennan, P., Foretova, L., Maynadié, M., Becker, N., Nieters, A., Staines, A., Campagna, M., Chiu, B., Clavel, J., de Sanjose, S., Hartge, P., Holly, E.A., Bracci, P., Linet, M.S., Monnereau, A., Orsi, L., Purdue, M.P., Rothman, N., Lan, Q., Kane, E., Costantini, A.S., Miligi, L., Spinelli, J.J., Zheng, T., Cocco, P., Kricker, A. |
Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: |
Oncology
Adult Male medicine.medical_specialty Adolescent Health Toxicology and Mutagenesis MEDLINE Review Barbering 03 medical and health sciences 0302 clinical medicine immune system diseases Risk Factors Internal medicine hemic and lymphatic diseases medicine Humans 030212 general & internal medicine Aged Aged 80 and over business.industry Extramural Public health Lymphoma Non-Hodgkin Public Health Environmental and Occupational Health Case-control study Agriculture Middle Aged medicine.disease 030210 environmental & occupational health Seguretat en el treball Lymphoma Malaltia de Hodgkin Occupational Diseases Pooled analysis Meta-analysis Case-Control Studies Textile Industry Hodgkin lymphoma Industrial safety Female Hodgkin's disease business Occupation - non-hodgkin lymphoma |
Zdroj: | Environmental Health Perspectives Recercat. Dipósit de la Recerca de Catalunya instname Dipòsit Digital de la UB Universidad de Barcelona Environmental Health Perspectives, 124(4), 396. Public Health Services, US Dept of Health and Human Services |
ISSN: | 1552-9924 0091-6765 |
Popis: | Background: Various occupations have been associated with an elevated risk of non-Hodgkin lymphoma (NHL), but results have been inconsistent across studies. Objectives: We investigated occupational risk of NHL and of four common NHL subtypes with particular focus on occupations of a priori interest. Methods: We conducted a pooled analysis of 10,046 cases and 12,025 controls from 10 NHL studies participating in the InterLymph Consortium. We harmonized the occupational coding using the 1968 International Standard Classification of Occupations (ISCO-1968) and grouped occupations previously associated with NHL into 25 a priori groups. Odds ratios (ORs) adjusted for center, age, and sex were determined for NHL overall and for the following four subtypes: diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), and peripheral T-cell lymphoma (PTCL). Results: We confirmed previously reported positive associations between NHL and farming occupations [field crop/vegetable farm workers OR = 1.26; 95% confidence interval (CI): 1.05, 1.51; general farm workers OR = 1.19; 95% CI: 1.03, 1.37]; we also confirmed associations of NHL with specific occupations such as women’s hairdressers (OR = 1.34; 95% CI: 1.02, 1.74), charworkers/cleaners (OR = 1.17; 95% CI: 1.01, 1.36), spray-painters (OR = 2.07; 95% CI: 1.30, 3.29), electrical wiremen (OR = 1.24; 95% CI: 1.00, 1.54), and carpenters (OR = 1.42; 95% CI: 1.04, 1.93). We observed subtype-specific associations for DLBCL and CLL/SLL in women’s hairdressers and for DLBCL and PTCL in textile workers. Conclusions: Our pooled analysis of 10 international studies adds to evidence suggesting that farming, hairdressing, and textile industry–related exposures may contribute to NHL risk. Associations with women’s hairdresser and textile occupations may be specific for certain NHL subtypes. Citation: ‘t Mannetje A, De Roos AJ, Boffetta P, Vermeulen R, Benke G, Fritschi L, Brennan P, Foretova L, Maynadié M, Becker N, Nieters A, Staines A, Campagna M, Chiu B, Clavel J, de Sanjose S, Hartge P, Holly EA, Bracci P, Linet MS, Monnereau A, Orsi L, Purdue MP, Rothman N, Lan Q, Kane E, Seniori Costantini A, Miligi L, Spinelli JJ, Zheng T, Cocco P, Kricker A. 2016. Occupation and risk of non-Hodgkin lymphoma and its subtypes: a pooled analysis from the InterLymph Consortium. Environ Health Perspect 124:396–405; http://dx.doi.org/10.1289/ehp.1409294 |
Databáze: | OpenAIRE |
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