Stimulation of subthalamic fibre tracts reduces dyskinesias in STN-DBS
| Autor: | M. Wasner, Jan Herzog, S. Wailke, Frank Steigerwald, Jens Volkmann, M. O. Pinsker, Günther Deuschl |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Deep brain stimulation medicine.medical_treatment Deep Brain Stimulation Central nervous system Stimulation Neurological disorder Central nervous system disease White matter Nerve Fibers Postoperative Complications Subthalamic Nucleus otorhinolaryngologic diseases Medicine Humans Neurologic Examination Postoperative Care Dyskinesias business.industry Parkinson Disease Middle Aged medicine.disease nervous system diseases Subthalamic nucleus surgical procedures operative medicine.anatomical_structure nervous system Neurology Dyskinesia Anesthesia Female Neurology (clinical) medicine.symptom Psychology business therapeutics Neuroscience |
| Zdroj: | Movement disorders : official journal of the Movement Disorder Society. 22(5) |
| ISSN: | 0885-3185 |
| Popis: | Rarely, the postoperative management of patients with subthalamic deep brain stimulation (STN-DBS) is complicated by pharmacologically intractable dyskinesias. Here we report that in three of these patients additional stimulation of a proximal contact located within the subthalamic white matter may lead to a significant reduction of dyskinesias associated with STN-DBS. We propose that pallidofugal fiber tracts play a major role in the etiopathology of dyskinesias and their blockade through DBS may explain our observations. |
| Databáze: | OpenAIRE |
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