The association between cardiac injury and outcomes in hospitalized patients with COVID-19
| Autor: | Haleh Ashraf, Mohammad Talebpour, Zahra Shajari, Mahnaz Montazeri, Hedieh Moradi, Abbas Soleimani, Alireza Oraii, Mahsa Akhbari, Shahrokh Karbalai Saleh, Pargol Balali, Azar Hadadi, Azadeh Sadat Naseri |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Pneumonia Viral Iran 030204 cardiovascular system & hematology Cardiovascular Statistics Nonparametric 03 medical and health sciences 0302 clinical medicine Internal medicine Outcome Assessment Health Care medicine Internal Medicine Humans Prospective Studies 030212 general & internal medicine Leukocytosis Mortality Prospective cohort study Pandemics Survival rate Aged Proportional Hazards Models Oxygen saturation (medicine) biology SARS-CoV-2 business.industry Proportional hazards model Mortality rate COVID-19 Middle Aged Troponin Im - Original Hospitalization Survival Rate Heart Injuries Cardiology biology.protein Emergency Medicine Population study Female medicine.symptom Coronavirus Infections business |
| Zdroj: | Internal and Emergency Medicine |
| ISSN: | 1970-9366 1828-0447 |
| DOI: | 10.1007/s11739-020-02466-1 |
| Popis: | In this study, we aimed to assess the association between development of cardiac injury and short-term mortality as well as poor in-hospital outcomes in hospitalized patients with COVID-19. In this prospective, single-center study, we enrolled hospitalized patients with laboratory-confirmed COVID-19 and highly suspicious patients with compatible chest computed tomography features. Cardiac injury was defined as a rise of serum high sensitivity cardiac Troponin-I level above 99th percentile (men: > 26 ng/mL, women: > 11 ng/mL). A total of 386 hospitalized patients with COVID-19 were included. Cardiac injury was present among 115 (29.8%) of the study population. The development of cardiac injury was significantly associated with a higher in-hospital mortality rate compared to those with normal troponin levels (40.9% vs 11.1%, p value |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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