Synthesis and biological activity of novel thiazolidinediones
| Autor: | M. R. Sarma, C. Prabhakar, K. Sahadev, C. Seshagiri Rao, G. Om Reddy, Ranjan Chakrabarti, G. Madhusudhan, Ch. Maheedhara Reddy, T.Dileep Kumar, Ramanujam Rajagopalan |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Blood Glucose
Male medicine.drug_class medicine.medical_treatment Nabumetone Clinical Biochemistry Pharmaceutical Science Biochemistry Chemical synthesis Mice Structure-Activity Relationship Troglitazone Drug Discovery medicine Animals Edema Hypoglycemic Agents Thiazolidinedione Chromans Rats Wistar Molecular Biology Chemistry Insulin Organic Chemistry Anti-Inflammatory Agents Non-Steroidal Biological activity Thiophene derivatives Butanones Rats Thiazoles Molecular Medicine Female Thiazolidinediones Pharmacophore |
| Zdroj: | Bioorganicmedicinal chemistry letters. 8(19) |
| ISSN: | 0960-894X |
| Popis: | Novel compounds having a dual pharmacophore were synthesised and evaluated for their insulin sensitiser and anti-inflammatory properties in different animal models. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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