Choroidal area assessment in various fundus sectors of patients at different stages of primary open-angle glaucoma by using enhanced depth imaging optical coherence tomography
| Autor: | Jing-Min Guo, Hong Zhang, Xiaoqin Yan, Yinwei Song, Mu Li |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Visual acuity primary open-angle glaucoma Open angle glaucoma genetic structures Fundus Oculi Glaucoma Observational Study Fundus (eye) 03 medical and health sciences 0302 clinical medicine Optical coherence tomography Ophthalmology medicine Humans optical coherence tomography medicine.diagnostic_test business.industry Choroid General Medicine Middle Aged medicine.disease eye diseases choroidal area Visual field 030104 developmental biology medicine.anatomical_structure Case-Control Studies 030221 ophthalmology & optometry Female Enhanced depth imaging sense organs medicine.symptom business Glaucoma Open-Angle Tomography Optical Coherence Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 |
| Popis: | To compare the choroidal area in different eye fundus sectors of subjects with normal eyes, early-stage primary open-angle glaucoma (POAG) eyes, and 10° tubular visual field POAG eyes using enhanced depth imaging optical coherence tomography. Twenty-five normal, 25 early-stage POAG, and 25 ten-degree tubular visual field POAG eyes were recruited. Enhanced depth imaging optical coherence tomography was used to measure the choroidal area in different fundus sectors (fovea; 10° superior, inferior, temporal, and 24° superior, inferior, temporal, nasal to the fovea) and the peripapillary sector. There were neither significant differences in the choroidal area at any of the 8 measured fundus sectors, nor significant differences in the percentage change between the choroidal area of the fovea and other 7 measured fundus sectors among the 3 groups (all P > 0.05). For the total peripapillary choroidal area, no significant difference was found among the 3 groups (P > 0.05); however, the temporal peripapillary choroidal area of 10° tubular visual field POAG eyes was significantly thicker than that of normal eyes (4,46,213 ± 1,16,267 vs 3,74,164 ± 1,21,658 μm2; P = 0.048). Our study showed that there was no significant difference in the choroidal area of the 8 measured fundus sectors among normal, early-stage POAG, and 10° tubular visual field POAG eyes, suggesting that there might be no blood redistribution from the peripheral choroid to the subfoveal choroid. However, the thicker temporal peripapillary choroidal area might play a role in the central visual acuity protection in patients with POAG. |
| Databáze: | OpenAIRE |
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