Fine-needle aspiration biopsy of ki-1-positive anaplastic large-cell lymphoma
| Autor: | Bo Hainau, Abdulrazzaq Haider, Fouad Al Dayel, Mohammed Akhtar, Muhammad Ashraf Ali, John Antonius |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Histology Adolescent Ki-1 Antigen Pathology and Forensic Medicine Antigens CD Antigens Neoplasm Cytology Biopsy medicine Null cell Humans Neoplasm Anaplastic large-cell lymphoma Aged medicine.diagnostic_test business.industry Biopsy Needle Antibodies Monoclonal General Medicine Middle Aged medicine.disease Lymphoma Microscopy Electron Fine-needle aspiration Immunohistochemistry Female Lymphoma Large B-Cell Diffuse business |
| Zdroj: | Diagnostic Cytopathology. 8:242-247 |
| ISSN: | 1097-0339 8755-1039 |
| Popis: | Five cases of Ki-1-positive anaplastic large-cell lymphoma diagnosed by fine-needle aspiration biopsy are reviewed, and cytologic, histologic, and ultrastructural findings in these cases are correlated. In all cases, the diagnosis of anaplastic large-cell lymphoma was suggested on the basis of the morphological appearance in aspiration smears. This diagnosis was confirmed by immunohistochemistry, which revealed strong positivity of most of the cells by Ki-1 antibody. Two of the lymphomas were T-cell type, one was B-cell type, and the remaining 2 were composed of null cells. In 2 cases, intracytoplasmic inclusions were seen in some of the tumor cells in aspiration smears. These were ultrastructurally correlated with large lysosomal bodies of variable morphology. Fine-needle aspiration combined with immunohistochemistry may be an effective technique for diagnosing this neoplasm. © 1992 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
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