A stepwise approach to implementing pharmacogenetic testing in the primary care setting
| Autor: | Susanne B. Haga, Ebony B. Madden, Joshua C. Denny, Brian S. Decker, Kristin Weitzel, Toni I. Pollin, Aniwaa Owusu-Obeng, Eric Dietrich, John G. Gums, Barbara A. Bernhardt, Rebekah Ryanne Wu, Benjamin Q. Duong, Carol R. Horowitz, Noura S. Abul-Husn, Meghan J. Arwood |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Pharmacology
medicine.medical_specialty Primary Health Care business.industry Decision Making Primary care Precision medicine Pharmacogenomic Testing Test (assessment) Pharmacogenetics Pharmacogenomics Genetics Humans Molecular Medicine Medicine business Intensive care medicine Delivery of Health Care Special Report Pharmacogenetic Test Stepwise approach Patient education |
| Zdroj: | Pharmacogenomics |
| ISSN: | 1744-8042 1462-2416 |
| DOI: | 10.2217/pgs-2019-0053 |
| Popis: | Pharmacogenetic testing can help identify primary care patients at increased risk for medication toxicity, poor response or treatment failure and inform drug therapy. While testing availability is increasing, providers are unprepared to routinely use pharmacogenetic testing for clinical decision-making. Practice-based resources are needed to overcome implementation barriers for pharmacogenetic testing in primary care.The NHGRI’s IGNITE I Network (Implementing GeNomics In pracTicE; www.ignite-genomics.org ) explored practice models, challenges and implementation barriers for clinical pharmacogenomics. Based on these experiences, we present a stepwise approach pharmacogenetic testing in primary care: patient identification; pharmacogenetic test ordering; interpretation and application of test results, and patient education. We present clinical factors to consider, test-ordering processes and resources, and provide guidance to apply test results and counsel patients. Practice-based resources such as this stepwise approach to clinical decision-making are important resources to equip primary care providers to use pharmacogenetic testing. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|