Effects of monochromatic infrared phototherapy in patients with diabetic peripheral neuropathy: a systematic review and meta-analysis of randomized controlled trials
| Autor: | Graciele Sbruzzi, Maicon Falavigna, Caroline Cabral Robinson, Patrícia da Silva Klahr, Rodrigo Della Méa Plentz, Cinara Stein |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Sensorimotor peripheral neuropathy
medicine.medical_specialty MEDLINE Pain Tactile sensitivity 030209 endocrinology & metabolism Physical Therapy Sports Therapy and Rehabilitation law.invention 03 medical and health sciences 0302 clinical medicine Diabetic Neuropathies Randomized controlled trial law Diabetes mellitus medicine Humans Orthopedics and Sports Medicine In patient 030212 general & internal medicine Randomized Controlled Trials as Topic Foot business.industry Diabetes Rehabilitation Phototherapy medicine.disease Peripheral neuropathy Meta-analysis Neuropathic pain Physical therapy Systematic Review business |
| Zdroj: | Brazilian Journal of Physical Therapy |
| ISSN: | 1413-3555 |
| DOI: | 10.1016/j.bjpt.2017.05.008 |
| Popis: | Highlights • MIRE is an adjunctive phototherapy source approved by FDA to improve blood perfusion and reduce pain. • MIRE was associated with a modest short-term improvement in plantar tactile sensitivity, not sustained over time. • MIRE resulted in a less decrease in pain relief, possibly associated with initial improvement in plantar sensitivity. • Current quality of evidence is low and further studies are likely to change the estimated effect. Background Monochromatic infrared energy (MIRE) or phototherapy has been used to improve plantar sensitivity and pain in lower limbs of patients with diabetic sensorimotor peripheral neuropathy (DSPN), but the available primary results are inconsistent. Objective To review systematically the effects of MIRE on plantar sensitivity and neuropathic pain in patients with DSPN. Methods Medline, EMBASE, Cochrane CENTRAL, and Google Scholar were searched up to September 2016. Randomized controlled trials addressing the effects of MIRE on plantar sensitivity and neuropathic pain in patients with DSPN were selected. Study inclusion, risk of bias and quality assessment, and data extraction were completed by two independent reviewers. Results Of 2549 records identified, six studies met the selection criteria, with 304 patients (594 feet) randomized. MIRE was not associated with improvement in plantar tactile sensitivity (SMD = 0.22, 95%CI −0.07 to 0.51, low quality of evidence). Subgroups of studies with short-term (up to 2 weeks) follow-up showed significant improvement in plantar sensitivity (SMD = 0.41, 95% CI 0.18–0.64). Neuropathic pain increased significantly in patients who received MIRE (MD = 0.49, 95% CI 0.30–0.68, low quality of evidence). Conclusions There was limited evidence that MIRE results in short-term improvement of tactile sensitivity probably not sustained over time. Limited evidence also suggested that MIRE does not provide relief for neuropathic pain. As quality of evidence is low, further studies are likely to change the estimated effect. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect