Direct organocatalytic hydroalkoxylation of α,β-unsaturated ketones

Autor:	Rumpa Mondal, Dhevalapally B. Ramachary
Rok vydání:	2006
Předmět:	chemistry.chemical_classification Addition reaction Chemistry Organic Chemistry General Medicine Biochemistry Catalysis Amino acid chemistry.chemical_compound Transition metal Organocatalysis Drug Discovery Organic chemistry Amine gas treating Organic synthesis Bifunctional Hydroalkoxylation
Zdroj:	Tetrahedron Letters. 47:7689-7693
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2006.08.134
Popis:	The direct addition of a variety of alcohols to in situ activated olefins was observed in the presence of mild bifunctional amine/acid catalysts. Unlike existing methods, the reactions proceed at room temperature and in the absence of transition metals. The use of simple commercially available catalysts, amines and acids makes this an attractive method for the preparation of β-alkoxy ketones, which are prevalent targets and intermediates in organic synthesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a0b0d8ca269a500e8be67c510429fe https://doi.org/10.1016/j.tetlet.2006.08.134 Zobrazit plný text záznamu Full Text from ScienceDirect