Bovine viral diarrhea virus: Its effects on estradiol, progesterone and prostaglandin secretion in the cow
| Autor: | Bryan Charleston, M. C. Clarke, M. D. Fray, George E Mann |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
animal diseases viruses media_common.quotation_subject Ovary Viremia Luteal phase Biology Antibodies Viral Dinoprost Virus Prostaglandin secretion Andrology Leukocyte Count Food Animals Pregnancy Internal medicine medicine Animals Small Animals Pathogen Ovulation Progesterone media_common Estrous cycle Diarrhea Viruses Bovine Viral Estradiol Equine virus diseases Abortion Veterinary biochemical phenomena metabolism and nutrition medicine.disease medicine.anatomical_structure Endocrinology Bovine Virus Diarrhea-Mucosal Disease Cattle Female Animal Science and Zoology Infertility Female |
| Zdroj: | Theriogenology. 51:1533-1546 |
| ISSN: | 0093-691X |
| DOI: | 10.1016/s0093-691x(99)00096-5 |
| Popis: | Bovine viral diarrhea virus (BVDV) is a major cattle pathogen responsible for a spectrum of symptoms, including reproductive failure. This study was designed to establish the effects of BVDV infection on estradiol, progesterone and PGF2alpha secretion in the cow. Seven BVDV-free cows were challenged with non-cytopathogenic BVDV (strain Pe 515: 5x10(6) tissue culture infected dose50) so that peak viremia occurred during the initial phase of luteal development in a synchronized estrous cycle. Ovulation was also synchronized in 7 sham-infected animals. Within 2 wk of inoculation, viremia, leukopenia and serum neutralizing antibodies were recorded in all of the BVDV-infected cows but not the sham-infected animals. Between Day 4 and Day 9 post estrus the BVDV-infected cows had significantly (P0.01) lower plasma estradiol levels than the sham-infected animals. However, the BVDV infection did not alter rectal temperatures, plasma progesterone concentrations or PGF2alpha secretion 17, 18 and 19 d post estrus. These data highlight a potential causal link between BVDV viremia, endocrine dysfunction and poor fertility in the cow. |
| Databáze: | OpenAIRE |
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