The transcontinental variability of nonalcoholic fatty liver disease

Autor: Denise Siqueira Vanni, Abhijit Chowdhury, Arun J. Sanyal, Mohammed S. Siddiqui, José Tadeu Stefano, Sherry Boyett, Claudia P. Oliveira, Angelo H. Paredes, Lawrence Serfaty
Rok vydání: 2022
Předmět:
Zdroj: Hepatoma research. 6
ISSN: 2394-5079
Popis: To compare the phenotype of lean versus overweight (OW) and obese (OB) subjects with non-alcoholic fatty liver disease (NAFLD) across multiple continents.A retrospective study of histologically defined subjects from a single center each in France (Fr), Brazil (Br), India (In) and United States (US) was performed.A total of 70 lean [body mass index (BMI)25 kg/mThe phenotype of NAFLD in lean subjects varies by region. Some obese subjects with NAFLD are insulin-sensitive. We hypothesize that genetics and region-specific disease modifiers account for these differences.
Databáze: OpenAIRE