Synthesis of Mono-N-Methyl Aromatic Amines from Nitroso Compounds and Methylboronic Acid

Autor:	Aurelio G. Csaky, Silvia Roscales
Rok vydání:	2019
Předmět:	Methylboronic acid Reaction conditions Chemistry chemistry.chemical_compound Nitroso Compounds General Chemical Engineering Organic chemistry General Chemistry QD1-999 Article Triethylphosphite
Zdroj:	ACS Omega, Vol 4, Iss 9, Pp 13943-13953 (2019) ACS Omega
ISSN:	2470-1343
DOI:	10.1021/acsomega.9b01608
Popis:	The selective synthesis of mono-N-methyl aromatic amines was achieved by the reaction of aromatic nitroso compounds with methylboronic acid promoted by triethylphosphite under transition metal-free conditions. The target compounds are constructed efficiently without overmethylation, under environmentally benign reaction conditions that do not require bases or reductants and therefore are of interest in pharmaceutical, agricultural, and chemical industries.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6295078fd751b1e39aeaf57dbad523b2 https://doi.org/10.1021/acsomega.9b01608 Zobrazit plný text záznamu