Long-term epidural analgesia treatment in pre-eclamptic women: A preliminary trial
| Autor: | Celleno D, Andrea Tinelli, Antonio Malvasi, Raffaele Tinelli, F. Greco, Brizzi A |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
medicine.medical_specialty Sufentanil Pregnancy Trimester Third Birth weight medicine.medical_treatment Analgesic Pilot Projects Clonidine Drug Administration Schedule Catecholamines Pre-Eclampsia Pregnancy medicine Humans Ropivacaine Caesarean section Labor Induced Anesthetics Local Antihypertensive Agents business.industry Pregnancy Outcome Obstetrics and Gynecology medicine.disease Amides Surgery Analgesia Epidural Blood pressure Anesthesia Analgesia Obstetrical Drug Therapy Combination Female business Adrenergic alpha-Agonists Adjuvants Anesthesia medicine.drug |
| Zdroj: | Journal of Obstetrics and Gynaecology. 29:114-118 |
| ISSN: | 1364-6893 0144-3615 |
| DOI: | 10.1080/01443610802646892 |
| Popis: | Pre-eclampsia (PE) is a clinical pregnancy-related condition, characterised by an elevated blood pressure and proteinuria. The author treated selected cases of PE with long-term epidural analgesia (LTEA), that reduced labour pain and operated directly on the PE aetiopathogenesis, not on the symptoms. A total of 15 women with PE were hospitalised at 35-37 weeks of pregnancy, checked for blood pressure, liver and renal function, platelet count and had an epidural catheter inserted for a continuous administration of an analgesic mixture of Naropin, Sufentanil and Clonidine. The average weeks at delivery were 37 weeks and 1 day; 10 women had a spontaneous delivery and five a caesarean section: the mean birth weight was 2,906 g and the Apgar scores at 1 min and 5 min exceeded 7 in all cases. All the parameters improved after hospital admission and at discharge. All the patients were discharged in good condition and no patients needed supplementary antihypertensive treatment. The LTEA utilisation for 1 week is well tolerated and improves uteroplacental perfusion, but further studies and a larger number of patients are required to evaluate this pharmacological procedure and determine its place in the management of PE. |
| Databáze: | OpenAIRE |
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