We need to bring R0 < 1 to treat cancer too
| Autor: | Devabhaktuni Srikrishna, Kris Sachsenmeier |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Colorectal cancer T-Lymphocytes medicine.medical_treatment T cell Systems biology Immune checkpoint inhibitors Disease QH426-470 03 medical and health sciences 0302 clinical medicine Neoplasms Biomarkers Tumor Tumor Microenvironment medicine Genetics Humans Neoplasm Metastasis Molecular Biology Genetics (clinical) Neoplasm Staging business.industry Comment Disease Management Cancer Immunotherapy Models Theoretical medicine.disease Combined Modality Therapy 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis Cancer cell Cancer research Molecular Medicine Medicine Microsatellite Instability Disease Susceptibility business |
| Zdroj: | Genome Medicine, Vol 13, Iss 1, Pp 1-4 (2021) Genome Medicine |
| Popis: | If each cancer cell produces on average more than one cancer cell, we see a net growth of the tumors and metastases and vice versa. We review recent clinical results for microsatellite stable metastatic colorectal cancer (MSS-mCRC) suggesting immunotherapy combinations with personalized vaccines, checkpoint inhibitors, targeted therapies, multikinase inhibitors, chemotherapies, and radiation that simultaneously slow cancer cell growth rate and enhance T cell killing rate of cancer cells may in future synergize to control the disease. |
| Databáze: | OpenAIRE |
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