Approach to novel functional foods for stress control: 5. Antioxidant activity profiles of antidepressant herbs and their active components
| Autor: | Junji Terao, Rintaro Yamanishi, Mutsuko Shirai, Yoshichika Kawai |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Lipid Peroxides
Time Factors antidepressant activity antioxidant Antioxidant food.ingredient medicine.medical_treatment ved/biology.organism_classification_rank.species Pharmacology medicine.disease_cause PC12 Cells complex mixtures Antioxidants General Biochemistry Genetics and Molecular Biology Lipid peroxidation chemistry.chemical_compound food Nerve Growth Factor medicine Animals oxidative stress Apocynum venetum herb extract Plants Medicinal Dose-Response Relationship Drug biology Traditional medicine Plant Extracts Ginkgo biloba ved/biology PC-12 Hypericum perforatum Cell Differentiation General Medicine biology.organism_classification Antidepressive Agents Rats Linoleic Acids chemistry Apocynum Food Herb Antidepressant Quercetin Lipid Peroxidation Reactive Oxygen Species Hypericum Oxidative stress |
| Zdroj: | The Journal of Medical Investigation. 52:249-251 |
| ISSN: | 1349-6867 1343-1420 |
| DOI: | 10.2152/jmi.52.249 |
| Popis: | Oxidative stress is frequently mentioned in relation to the neurodegenerative diseases. This study examined the effect of three herb extracts, Hypericum perforatum, Ginkgo biloba L. and Apocynum venetum L., and their components on lipid hydroperoxide-induced oxidative stress in PC-12 cells. Among them, the extract of Apocynum venetum and its components showed the remarkable inhibitory effect, indicating that this herb extract serves as a protective agent against lipid peroxidation-related oxidative stress in CNS. Oxidative stress may be associated with the progress of depression, as this extract has been proposed to be an effective antidepresant herb. |
| Databáze: | OpenAIRE |
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