Menstrual cycle and its disorders in women with congenital heart disease
| Autor: | Drenthen, Willem, Hoendermis, Elke S., Moons, Philip, Heida, Karst Y., Roos-Hesselink, Jolien W., Mulder, Barbara J.M., Van Dijk, Arie P.J., Vliegen, Hubert W., Sollie, Krystyna M., Berger, Rolf M.F., Lely, A. Titia, Canobbio, Mary M., Pieper, Petronella G., Berger, Rudolphus |
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| Přispěvatelé: | Cardiology, Internal Medicine, Pediatrics, Cardiovascular Centre (CVC), Vascular Ageing Programme (VAP), ACS - Amsterdam Cardiovascular Sciences |
| Rok vydání: | 2008 |
| Předmět: |
Heart Defects
Congenital Adult Reoperation Pediatrics medicine.medical_specialty Heart disease media_common.quotation_subject Population Congenital Informed consent Medicine Humans Radiology Nuclear Medicine and imaging Heart lung and circulation [UMCN 2.1] Polymenorrhea education Amenorrhea Menorrhagia Menstrual cycle Menstruation Disturbances media_common Heart Defects Gynecology education.field_of_study Cardiovascular diseases [NCEBP 14] business.industry Medical record Age Factors General Medicine Middle Aged medicine.disease Oligomenorrhea Logistic Models Pediatrics Perinatology and Child Health Menarche Surgery Female medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Congenital Heart Disease, 3, 277-83 Congenital Heart Disease, 3(4), 277-283. Wiley-Blackwell Publishing Ltd Congenital Heart Disease, 3, 4, pp. 277-83 Congenital heart disease, 3(4), 277-283. Wiley-Blackwell |
| ISSN: | 1747-0803 1747-079X |
| Popis: | Item does not contain fulltext OBJECTIVES: To investigate the age at menarche, the prevalence of menstrual cycle (interval) disorders, and determinants in women with congenital heart disease (CHD). DESIGN: Using two CHD registries, 1802 (82%) of the 2196 women with CHD contacted (aged 18-58 years) provided written informed consent. After exclusion of patients with genetic disorders known to be associated with menstrual cycle disorders, 1593 eligible patients remained. Interviews by telephone and reviews of medical records were conducted. RESULTS: Overall, the age at menarche was slightly increased in women with CHD (13.3 vs. 13.1 years in the general population), mainly attributable to an increased prevalence of primary amenorrhea (n = 147; 9.2%). Other menstrual cycle disorders were documented: secondary amenorrhea (n = 181, 11.4%), polymenorrhea (n = 103, 6.5%), oligomenorrhea (n = 90, 5.6%), and menorrhagia (n = 117, 6.5%). The occurrence of these disorders also depended on the presence of cyanotic heart disease, surgical status, the number of surgical interventions, and the severity of CHD. DISCUSSION: Menstrual cycle disturbances, in particular primary amenorrhea, were frequently observed in this population. Patients with complex (cyanotic) heart disease needing repeated surgical interventions prior to menarche are especially at risk. |
| Databáze: | OpenAIRE |
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