Pattern of childhood malignant tumours in a teaching hospital in south‐western Nigeria

Autor: Adetoun S Sotimehin, A O J Agboola, Aderibigbe M O Shonubi, Temitope Y Oyebadejo, Folashade A Adekanmbi, Adekunbi A F Banjo, A A Musa, Anotu Mopelola Deji-Agboola
Rok vydání: 2009
Předmět:
Zdroj: Medical Journal of Australia. 190:12-14
ISSN: 1326-5377
0025-729X
DOI: 10.5694/j.1326-5377.2009.tb02254.x
Popis: Objective: To document general baseline data on the patterns of childhood malignant tumours at a teaching hospital in south-western Nigeria. Design, setting and participants: A retrospective study of childhood malignancy at Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria, during an 11-year period, from January 1996 to December 2006. Results: 77 children were diagnosed with malignant tumours (an average of seven diagnoses per year); 46 were boys (60%), giving a male-to-female ratio of 1.5 : 1. The age distribution of patients was 1–18 years. There were 42 diagnoses (55%) in the 1–5-year age group and 68 malignancies (88%) were diagnosed at ages of 12 years or younger. Lymphomas were the most prevalent malignancy identified, accounting for 31 diagnoses (40%). Burkitt’s lymphoma constituted the majority of malignancies (28 cases; 36%), followed by retinoblastoma (16 cases; 21%) and nephroblastoma (11 cases; 14%). Other malignancies included germ cell tumours (6), neuroblastomas (4), osteosarcomas (3), rhabdomyosarcomas (3) and non-Hodgkin’s lymphomas (3). One case each of medullary thyroid carcinoma, adenocarcinoma of the rectum, invasive mucinous carcinoma of the colon were also identified. Conclusion: These data suggest that Burkitt’s lymphoma is the most common childhood malignant tumour in our geographic area of south-western Nigeria. With the rising incidence of childhood malignancy in resource-poor countries, measuring the baseline occurrence of such tumours is imperative to provide
Databáze: OpenAIRE
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