Brain SPECT of Creutzfeldt-Jakob Disease
| Autor: | Young-do Kim, Shiro Tsuji, Masanari Kageyama, Hikaru Seto, Makoto Kawaguchi, Ryoko Shibata, Yasuyuki Tanii, Makoto Morijiri, Masashi Shimizu, Masao Kakishita, Naoto Watanabe, Yi-Wei Wu, Masayoshi Kurachi |
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| Rok vydání: | 1996 |
| Předmět: |
Male
Perfusion scanning Disease Creutzfeldt-Jakob Syndrome Iodine Radioisotopes Central nervous system disease Technetium Tc 99m Exametazime Degenerative disease Spect imaging Oximes mental disorders medicine Humans Radiology Nuclear Medicine and imaging Aged Tomography Emission-Computed Single-Photon business.industry Amphetamines Brain Organotechnetium Compounds General Medicine Middle Aged Iofetamine medicine.disease Magnetic Resonance Imaging nervous system diseases Atrophy Spongiform encephalopathy business Nuclear medicine Perfusion Technetium-99m |
| Zdroj: | Clinical Nuclear Medicine. 21:236-241 |
| ISSN: | 0363-9762 |
| DOI: | 10.1097/00003072-199603000-00010 |
| Popis: | SPECT imaging with I-123 IMP or Tc-99m HMPAO was performed in two patients with Creutzfeldt-Jakob disease to evaluate abnormalities in brain perfusion. In the first patient, there was decreased perfusion of the left frontal, parietal, and temporal lobes. CT and MRI were negative. In the second patient, there was patchy perfusion and slightly decreased perfusion of the right hemisphere. MRI revealed slight brain atrophy and bilateral high intensity areas in the basal ganglia on T2 weighted images. Subsequent SPECT imaging revealed severely decreased perfusion of the entire brain. Subsequent MRI demonstrated severe brain atrophy. |
| Databáze: | OpenAIRE |
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