Intracranial hypertension related to cerebral venous thrombosis; and acute ischemic stroke with micro-infarcts associated with IgG4-related disease
| Autor: | Oguzhan Coban, Erdem Tüzün, Esme Ekizoglu, Duygu Gezen Ak, Betül Baykan, Çağrı Ulukan, Erdinç Dursun |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Systemic disease Central nervous system Brain Ischemia 03 medical and health sciences 0302 clinical medicine Internal medicine parasitic diseases medicine Humans Acute ischemic stroke 030203 arthritis & rheumatology Venous Thrombosis integumentary system business.industry General Neuroscience Microcirculation fungi General Medicine Cerebral Infarction Middle Aged medicine.disease Eyelid swelling Stroke Venous thrombosis medicine.anatomical_structure Ischemic stroke Cardiology Immunohistochemistry IgG4-related disease Female Immunoglobulin G4-Related Disease Intracranial Hypertension business 030217 neurology & neurosurgery |
| Zdroj: | The International journal of neuroscience. 128(11) |
| ISSN: | 1563-5279 |
| Popis: | IgG4-related systemic disease (IgG4-RD) is characterized by an inflammatory reaction rich in IgG4-positive plasma cells, affecting multiple organs. This report describes a case who was diagnosed with IgG4-RD, having cerebral venous thrombosis and a subsequent acute ischemic stroke of undetermined cause. A 47-year-old woman presented with headache, visual disturbance and eyelid swelling and two years later she was admitted with acute attacks of mild left lower limb sensory-motor monoparesis. Indirect immunohistochemistry assay showed elevated level of IgG4, labeling neurons of the central nervous system, suggesting an immunological process possibly affecting vascular structures. Our experience suggests that IgG4-RD may be considered in patients with ischemic stroke and cerebral venous system involvement. |
| Databáze: | OpenAIRE |
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