Escherichia coli antimicrobial resistance increased faster among geriatric outpatients compared with adult outpatients in the USA, 2000-10
| Autor: | Alexis M. G. Baird, Ronald N. Master, Jose Bordon, Guillermo V. Sanchez, Richard B. Clark, Spencer J. E. Adams |
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| Rok vydání: | 2013 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty Adolescent Urinary system Urine Microbial Sensitivity Tests Microbiology Young Adult Antibiotic resistance Ampicillin Internal medicine Drug Resistance Bacterial Outpatients medicine Escherichia coli Prevalence Humans Pharmacology (medical) Escherichia coli Infections Aged Pharmacology Geriatrics Aged 80 and over business.industry Sulfamethoxazole Middle Aged Trimethoprim United States Anti-Bacterial Agents Ciprofloxacin Infectious Diseases Urinary Tract Infections Female business medicine.drug |
| Zdroj: | The Journal of antimicrobial chemotherapy. 68(8) |
| ISSN: | 1460-2091 |
| Popis: | OBJECTIVES Few studies have examined Escherichia coli antimicrobial resistance across age groups over time. The objective of this study was to compare urinary E. coli antimicrobial resistance trends among adult and geriatric outpatients from 2000 to 2010. METHODS Antimicrobial susceptibility results for E. coli urine isolates from adult (aged 16-64 years) and geriatric (aged ≥65 years) outpatients were analysed using data from The Surveillance Network Database-USA. RESULTS Susceptibility test results from adult (n = 6 412 025) and geriatric (n = 3 395 297) outpatients showed that E. coli antimicrobial resistance increased faster among geriatric outpatients for all agents studied. The greatest increases in resistance over the study time period were for ciprofloxacin (9.4% and 23.5% increases among adult and geriatric individuals, respectively), trimethoprim/sulfamethoxazole (4.3% and 10.5%) and ampicillin (2.0% and 13.6%). CONCLUSIONS Urinary E. coli antimicrobial resistance increased faster among geriatric outpatients than adult outpatients in the USA. Rising antimicrobial resistance disproportionately affects geriatric populations and presents a threat to public health. |
| Databáze: | OpenAIRE |
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