The role of antibiotic prophylaxis on wound infection after mesh hernia repair under local anesthesia on an ambulatory basis
| Autor: | José L. Souto, Jaime Esteban, Octavio Frieyro, Angel Celdrán, José F. Señarís, José M. Rubio, Juan C. de la Pinta |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Cefazolin Hernia Inguinal Double-Blind Method medicine Humans Surgical Wound Infection Local anesthesia Hernia Prospective Studies Antibiotic prophylaxis Aged business.industry Prostheses and Implants Ambulatory Surgical Procedure Antibiotic Prophylaxis Middle Aged Surgical Mesh medicine.disease Hernia repair Surgery Anti-Bacterial Agents Inguinal hernia Surgical mesh Ambulatory Surgical Procedures Anesthesia Female business medicine.drug Anesthesia Local |
| Zdroj: | Hernia : the journal of hernias and abdominal wall surgery. 8(1) |
| ISSN: | 1265-4906 |
| Popis: | Mesh prosthesis, local anesthesia, and ambulatory care have been widely introduced in recent decades in the treatment of inguinal hernia. The use of antibiotic prophylaxis during open inguinal hernia repair has been controversial. No prospective trial has been conducted to assess the role of antibiotic prophylaxis in patients operated on for inguinal hernia under the above-mentioned conditions. A prospective, randomized, double-blinded trial was initiated to assess the efficacy of antibiotic prophylaxis in the prevention of wound infection during open mesh inguinal hernia repair under local anesthesia on an ambulatory basis. Ninety-nine consecutive hernia repairs were randomized to receive 1 g of parenteral Cefazolin preoperatively or a placebo. No wound infections existed in the therapeutic group (0/50). Four infections appeared in the control group (4/49), and the study was suspended for ethical reasons when differences reached values close to statistical significance ( P=0.059). We conclude that a single dose of intravenous Cefazolin decreases the risk of wound infection during open mesh inguinal hernia repair under local anesthesia on an ambulatory basis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink