The study of intramolecular tandem radical cyclizations of acylsilanes with radicalphiles attached on silicon

Autor:	Yeun-Min Tsai, Kuo-Hsiang Tang, Fang-Yu Liao
Rok vydání:	2005
Předmět:	Silylation Tandem Silicon Chemistry Organic Chemistry Hydroxy group chemistry.chemical_element General Medicine Brook rearrangement Medicinal chemistry Biochemistry Silyl ether chemistry.chemical_compound Group (periodic table) Intramolecular force Drug Discovery Polymer chemistry Organic chemistry
Zdroj:	Tetrahedron. 61:2037-2045
ISSN:	0040-4020
DOI:	10.1016/j.tet.2004.12.053
Popis:	Radical cyclizations of acylsilanes with radicalphilic pendant introduced on silicon proceeded in a tandem fashion to give spiro products containing a cyclic silyl ether skeleton. Because the alkoxysilyl group can be replaced with a hydroxy group through oxidation, the spiro silyl ethers can be converted into diols. In the case with a radical intermediate carrying 2-oxa-3-sila-6-heptenyl skeleton, products derived from 1,7-endo cyclization were obtained in good yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626a5996f5943c33da855ff3aac1ee59 https://doi.org/10.1016/j.tet.2004.12.053 Zobrazit plný text záznamu Full Text from ScienceDirect