Cerebrospinal Fluid C-Reactive Protein Measurement--A Bedside Test in the Rapid Diagnosis of Bacterial Meningitis
| Autor: | Ragini Macaden, D. M. Meundi, T. S. Raghuveer, M. John, M. Yeswanth, I. S. Raj |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Pathology
medicine.medical_specialty Tuberculous meningitis Diagnosis Differential Epilepsy Cerebrospinal fluid medicine Humans Meningitis Child Developing Countries CSF albumin biology business.industry Viral encephalitis C-reactive protein Infant Newborn Infant Bacterial Infections medicine.disease Latex fixation test C-Reactive Protein Infectious Diseases Child Preschool Pediatrics Perinatology and Child Health biology.protein business Latex Fixation Tests |
| Zdroj: | Journal of Tropical Pediatrics. 36:213-217 |
| ISSN: | 1465-3664 0142-6338 |
| Popis: | C-reactive protein (C-RP) determinations were performed by the Latex agglutination method on the cerebrospinal fluid (CSF) samples of 212 patients with clinical features suggestive of meningitis. Patients were grouped as follows Group I: bacterial meningitis and partially treated bacterial meningitis (n = 22). Group II: viral encephalitis (n = 11). Group III: tuberculous meningitis (n = 18). Group IV: (i) febrile convulsions (n = 87); (ii) epileptic seizures (n = 70); (iii) intracranial haemorrhage (n = 4). C-RP was a better indicator of bacterial meningitis (sensitivity 91 per cent) than the Gram's stain (sensitivity 46 per cent). C-RP was positive in 91 per cent of patients in Group I, none in Groups II and III and 0.6 per cent in Group IV. C-RP determination in CSF proved to be a useful indicator of bacterial meningitis and served to distinguish it from viral encephalitis, tuberculous meningitis, febrile convulsions and other central nervous system disorders. |
| Databáze: | OpenAIRE |
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