First complete genome sequence of parainfluenza virus 5 isolated from lesser panda
| Autor: | Junqiong Zhai, He Zhang, Xia Zhou, Shao-Lun Zhai, Zou Shuzhan, Man-Lin Luo, He-Xing Wang, Tao Lin, Bing Li, Wu Chen, Meng-Fan Wu, Jiankui Liu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Sequence analysis Complete Genome Sequence Sequence alignment Genome Viral Genetic analysis Genome Cell Line 03 medical and health sciences Simian Virus Canine Distemper Virus Annotated Sequence Record Virology biology.animal Chlorocebus aethiops Animals Natural reservoir Gene Vero Cells Whole genome sequencing Nasal Swab biology Base Sequence Close Genetic Relationship General Medicine Rubulavirus Infections Sequence Analysis DNA 030104 developmental biology DNA Viral Parainfluenza Virus 5 Ailuridae Animals Zoo Lesser panda |
| Zdroj: | Archives of Virology |
| ISSN: | 1432-8798 0304-8608 |
| Popis: | Parainfluenza virus 5 (PIV5) is widespread in mammals and humans. Up to now, there is little information about PIV5 infection in lesser pandas. In this study, a PIV5 variant (named ZJQ-221) was isolated from a lesser panda with respiratory disease in Guangzhou zoo in Guangdong province, southern China. The full-length genome of ZJQ-221 was found to be 15,246 nucleotides and consisted of seven non-overlapping genes encoding eight proteins (i.e., NP, V, P, M, F, SH, HN and L). Sequence alignment and genetic analysis revealed that ZJQ-221 shared a close relationship with a PIV5 strain of canine-origin (1168-1) from South Korea. The findings of this study confirm the presence of PIV5 in lesser panda and indicate this mammal as a possible natural reservoir. Furthermore they highlight the urgent need to strengthen viral surveillance and control of PIV5 in zoo animals. Electronic supplementary material The online version of this article (doi:10.1007/s00705-017-3245-0) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink