Functionalized nanofibers as drug-delivery systems for osteochondral regeneration

Autor:	Patcharakamon Nooeaid, Eva Filová, Eva Prosecká, Matej Buzgo, Evžen Amler, Alois Nečas, Aldo R. Boccaccini, Michala Rampichová
Rok vydání:	2014
Předmět:	Bone Regeneration Materials science Regeneration (biology) Nanofibers Biomedical Engineering Medicine (miscellaneous) Bioengineering Nanotechnology Development Electrospinning Cartilage Drug Delivery Systems Nanofiber Drug delivery Animals Humans General Materials Science Bone regeneration
Zdroj:	Nanomedicine. 9:1083-1094
ISSN:	1748-6963 1743-5889
DOI:	10.2217/nnm.14.57
Popis:	A wide range of drug-delivery systems are currently attracting the attention of researchers. Nanofibers are very interesting carriers for drug delivery. This is because nanofibers are versatile, flexible, nanobiomimetic and similar to extracellular matrix components, possible to be functionalized both on their surface as well as in their core, and also because they can be produced easily and cost effectively. There have been increasing attempts to use nanofibers in the construction of a range of tissues, including cartilage and bone. Nanofibers have also been favorably engaged as a drug-delivery system in cell-free scaffolds. This short overview is devoted to current applications and to further perspectives of nanofibers as drug-delivery devices in the field of cartilage and bone regeneration, and also in osteochondral reconstruction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625dd7b81c591c9700d6277d35dcae74 https://doi.org/10.2217/nnm.14.57 Zobrazit plný text záznamu